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| 甘精胰岛素加阿卡波糖对2型糖尿病患者血糖的影响 | |
| 引用本文： | 薛腊梅,张如意. 甘精胰岛素加阿卡波糖对2型糖尿病患者血糖的影响[J]. 宁夏医学杂志, 2011, 33(9): 833-835 |
| 作者姓名： | 薛腊梅 张如意 |
| 作者单位： | 宁夏医科大学附属医院,宁夏,银川,750004 |
| 摘 要： | 目的比较口服降糖药血糖控制不好的2型糖尿病患者使用甘精胰岛素（来得时）加阿卡波糖（拜糖苹）或精蛋白生物合成人胰岛素（诺和灵30R）治疗,对血糖控制、血糖波动及低血糖的影响。方法 60例口服口服降糖药治疗的2型糖尿病患者分为两组,分别使用甘精胰岛素加阿卡波糖和精蛋白生物合成人胰岛素治疗,治疗前后用动态血糖监测仪监测患者血糖水平,观察日最大血糖波动幅度（LAGE）、餐后血糖波动幅度（PPGE）及空腹血糖变异系数（CV-FPG）的变化,同时观察夜间低血糖发生的次数及持续时间。结果甘精胰岛素加阿卡波糖组LAGE、PPGE及CV-FPG均低于精蛋白生物合成人胰岛素组（P〈0.05）;甘精胰岛素加阿卡波糖组夜间低血糖发生的次数及持续时间均低于精蛋白生物合成人胰岛素组（P〈0.05）。结论甘精胰岛素加阿卡波糖治疗2型糖尿病患者,既能减少血糖波动、稳定控制血糖,又可减少夜间低血糖的发生,有良好的安全性。 |
| 关 键 词： | 2型糖尿病 血糖波动 甘精胰岛素 阿卡波糖 |
Effect of the blood glucose in type 2 diabetes mellitus by glargine plus acarbose |
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| XUE La-mei,ZHANG Ru-yi. Effect of the blood glucose in type 2 diabetes mellitus by glargine plus acarbose[J]. Ningxia Medical Journal, 2011, 33(9): 833-835 | |
| Authors: | XUE La-mei ZHANG Ru-yi |
| Affiliation: | XUE La-mei,ZHANG Ru-yi.(The Affiliated Hospital of Ningxia Medical University,Yinchuan 750004,China) |
| Abstract: | Objective To compare the effects of blood glucose and hypoglycemia in the type 2 diabetes mellitus(T2DM) treated with glargine plus acarbose or 70% human insulin isophane and 30% human insulin.Methods 60 patients with T2DM were inadequately controlled by OADS,and the patients were randomly assigned into two groups treated with glargine plus acarbose or 70% human insulin isophane and 30% human insulin.BG was monitored with continues glucose monitoring system,and then the maximal excursion of variation of BG(... |
| Keywords: | Diabetes mellitus Blood glucose excursion Glargine Acabose |
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