| 正交试验优选养心方煎剂煎煮工艺 |
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| 引用本文： | 缪红,王一鸣. 正交试验优选养心方煎剂煎煮工艺[J]. 中国药房, 2010, 0(19): 1757-1758 |
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| 作者姓名： | 缪红 王一鸣 |
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| 作者单位： | 上海市黄浦区中西医结合医院药剂科; |
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| 摘 要： | 目的:优选养心方煎剂的煎煮工艺。方法:采用中药自动煎药包装机,以养心方煎剂中有效成分黄芪甲苷含量为指标,以煎煮时间、加水量和浸泡时间为考察因素,采用L(934)正交试验优选最佳煎煮条件。结果:对黄芪甲苷提取量影响顺序为煎煮时间>浸泡时间>加水量,其中煎煮时间有显著性差异。养心方煎剂最佳煎煮条件为煎煮时间60min,加水量4倍,浸泡时间60min。结论:该煎煮方法稳定、可行、易操作,适用于基层医院规模化制备养心方煎剂。
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| 关 键 词： | 养心方 正交试验 高效液相色谱法 黄芪甲苷 煎煮工艺 |
Optimization of Decoction Technology of Yangxinfang Decoction by Orthogonal Experiment |
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| MIAO Hong,WANG Yi-ming. Optimization of Decoction Technology of Yangxinfang Decoction by Orthogonal Experiment[J]. China Pharmacy, 2010, 0(19): 1757-1758 |
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| Authors: | MIAO Hong WANG Yi-ming |
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| Affiliation: | MIAO Hong,WANG Yi-ming(Dept.of Pharmacy,Shanghai Huangpu District Hospital of Integrated Traditional , Western Medicine,Shanghai 200010,China) |
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| Abstract: | OBJECTIVE:To optimize the decoction technology of Yangxinfang decoction.METHODS:The decoction techno-logy of Yangxinfang decoction was optimized by L9(34) orthogonal experiment with the content of astragaloside as index and with decoction time,the quantity of added water,immersion time as factors.RESULTS:On the impact of extraction astragaloside order:decoction time>soaking time>the quantity of added water.The best extraction process is to extract herb with 4 times of water,immerse for 60 min,decoct for 60 ... |
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| Keywords: | Yangxinfang Orthogonal experiment HPLC Astragaloside Decoction technology |
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