| 抑癌基因p16与肿瘤基因治疗 |
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| 引用本文： | 熊光武,王世阆. 抑癌基因p16与肿瘤基因治疗[J]. 实用妇产科杂志, 2002, 18(4): 210-212 |
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| 作者姓名： | 熊光武 王世阆 |
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| 作者单位： | 1. 第三军医大学西南医院,重庆,400038
2. 四川大学华西第二医院,四川,成都,610041 |
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| 摘 要： | 在肿瘤发生、发展过程中 ,癌基因的激活和抑癌基因的失活是细胞癌变的分子基础。p1 6基因是继 p53 和 RB基因之后发现的又一重要的抑癌基因。本文就 p1 6基因的结构、功能异常 ,及其相关的肿瘤基因治疗进行简要概述
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| 关 键 词： | p16基因 肿瘤 基因治疗 |
| 文章编号： | 1004-6946(2002)04-210-03 |
| 修稿时间： | 2001-04-13 |
Tumor Suppressor Gene p16 and Genetherapy of Cancer |
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| XIONG Guang-wu ,WANG Shi-lang. Tumor Suppressor Gene p16 and Genetherapy of Cancer[J]. Journal of Practical Obstetrics and Gynecology, 2002, 18(4): 210-212 |
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| Authors: | XIONG Guang-wu WANG Shi-lang |
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| Affiliation: | XIONG Guang-wu 1,WANG Shi-lang 2 |
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| Abstract: | The activation of oncogene and inactivation of tumor suppressor gene were known as oncogenesis molecular mechanism of cellular cancerization.Of the known tumor suppressor gene,p 16 is as important as p53 and RB.In this review,we have summarized the structure,dysfunction and relevant gengetherapy of p 16. |
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| Keywords: | p 16gene Tumor Gene therapy |
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