咪达唑仑口服镇静术在不同年龄段儿童口腔治疗中的效果评价

目的 总结咪达唑仑口服镇静术对口腔诊疗不配合的儿童患者的临床效果,探讨年龄因素对咪达唑仑治疗效果和安全性的影响.方法 选取109例对口腔诊疗不配合的儿童患者,在门诊环境下实施咪达唑仑口服镇静术辅助诊疗,给药剂量为0.50～0.75 mg/kg,记录各项评价指标并对≤3岁组(40例)和＞3岁组(69例)的治疗效果和安全性进行分析、比较.结果 镇静治疗总成功率为71%(77/109),≤3岁组治疗成功率[58%(23/40)]显著低于3岁以上组[78%(54/69)](x2=5.26,P＜0.05);总不良反应发生率为17%(19/109),≤3岁组不良反应发生率[28%(11/40)]显著高于3岁以上组[12%(8/69)],x2=4.24,P＜0.05.结论 咪达唑仑口服镇静术对3岁以上患者治疗效果好,不良反应相对少;口服咪达唑仑0.50～0.75 mg/kg的剂量范围安全有效.

Evaluation of oral midazolam conscious sedation in different age groups in pediatric dentistry

Objective To summarize the effect of oral midazolam sedation in a group of uncooperative patients in pediatric dentistry and analyze the influence of age on treatment results and safety.Methods Oral midazolam conscious sedation (dosages range: 0. 50-0. 75 mg/kg) was applied to 109 uncooperative pediatric patients in outpatient department. The patients were divided into two age groups:group A (under 3 years) and group B (over 3 years). Treatment results and safety were statistically analyzed. Results The mean success rate was 71% (77/109), which was higher in group B[78%(54/69)]than in group A[58% (23/40)]. The incidence of adverse reactions was 17% (19/109),which was higher in group A [28% (11/40)] than in group B [12% ( 8/69 )]. Conclusions Oral midazolam conscious sedation at a dosage range of 0. 50-0. 75 mg/kg is more effective and safe in pediatric dental patients over 3 years of age.