荞麦叶总黄酮对糖尿病并高脂血症大鼠血糖、血脂及血液流变性的影响

目的 :研究荞麦叶总黄酮 (TFBL)对糖尿病并高脂血症大鼠血糖、血脂、脂质过氧化产物丙二醛 (MDA)及血液流变性的影响。方法 :用链脲佐菌素和高脂饲料诱发大鼠糖尿病及高脂血症 ,口服TF BL治疗 12周 ,观察其对糖尿病并高脂血症大鼠的治疗作用。结果 :TFBL能明显降低高脂血症和糖尿病大鼠的血清LDL C ,升高HDL C ,降低血糖 ,改善糖耐量。降低血清MDA含量 ,降低血粘度。结论 :TFBL具有降血糖、调血脂、抗氧化、改善胰岛素抵抗和血液流变性的作用

Effects of Total Flavones from Buckwheat Leaf on Serum Glucose , Serum Lipid and Hemorrheological proparty in Rats with Diabetis and Hyperlipidemia

Objective: The effects of total flavones from buckwheat leaves (TFBL) on serum glucose,blood lipid,MDA and hemorrheological proparty were studied in the rats with diabeter and hyperlipidemia.Method: The model rats with diabetes and hyperlipidemia were induced by feeding on streptozotocin and high lipid feed and later were treated by taking TFBL for 12 weeks.Results: TFBL remarkably reduced LDL C and serum glucase, raised HDL C, improved lipid metabolic disorder and glucose tolerance. TFBL could also remarkably lower the content of MDA and improve hemorrheology indexes. Conclusion: TFBL had the effects of lowing serum glucose, blood lipid, anti lipid peroxidation, improve hemorrheological proparty and increase insulin sensitivity.