| 利培酮与舒必利治疗精神分裂症对照研究 |
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| 引用本文： | 翁正 张敬悬. 利培酮与舒必利治疗精神分裂症对照研究[J]. 临床精神医学杂志, 1999, 9(6): 331-333 |
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| 作者姓名： | 翁正 张敬悬 |
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| 作者单位： | 山东省精神卫生中心，山东省精神卫生中心，山东淄博市精神病医院，山东淄博市精神病医院，滨州地区第三人民医院，滨州地区第三人民医院，潍坊市精神卫生中心，潍坊市精神卫生中心，枣庄市立二院，枣庄市立二院，济宁市精神病防治院，济宁市精神病防治院，临沂地区复退军人精神病院，临沂地 |
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| 摘 要： | 目的：比较利培酮与舒必利对精神分裂症的临床疗效及对各症状群的作用特点，观察其副作用方法：将符合入级标准的精神分裂症患者随机分为利培酮与舒必利两组，用阳必瑟阴性症状量表（ＰＡＮＳＳ）、简明精神病评定量表（ＢＰＲＳ）、临床疗效总评（ＣＧＩ）、阴性症状量表（ＳＡＮＳ）和副反应量表（ＴＥＳＳ）等评定其疗效和副反应。结果：利培酮组疗效优于舒必利组，对阴性症状的效果更显著。ＴＥＳＳ总分两组间差异无显著性。结论
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| 关 键 词： | 利培酮 舒必利 精神分裂症 药物疗法 |
A controlled trial comparing the efficacy of risperidone and sulpiride in the treatment of schizophrenia |
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| Weng Zheng,Zhang Jingxuan,Han Kehe,et al.. A controlled trial comparing the efficacy of risperidone and sulpiride in the treatment of schizophrenia[J]. Journal of Clinical Psychological Medicine, 1999, 9(6): 331-333 |
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| Authors: | Weng Zheng Zhang Jingxuan Han Kehe et al. |
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| Affiliation: | Weng Zheng,Zhang Jingxuan,Han Kehe,et al.Shangdong Mental Health Centre,Jinan 250014 |
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| Abstract: | Objective:To study the efficacy and side effect of risperidone and sulpiride in the treatment of schizophrenia. Method:Patients with diagnosis of schizophrenia and fulfilling the admission criteria to the study were randomly assigned to two groups that were treated with either risperidone or sulpiride. The therapeutic response and side effects were evaluated with the PANSS, SANS, BPRS, CGI and TESS. Results:The overall therapeutic effect of risperidone were superior to that of sulpiride with significant difference as measured with the PANSS, SANS and CGI. However, there was on statistical difference in the TESS score between the two groups. Conclusion:Risperidone is superior than sulpiride in the treatment of schizophrenia,especially the negative symptoms. |
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| Keywords: | Risperidone Sulpiride Schizophrenia |
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