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文拉法辛与阿米替林治疗抑郁症对照研究
引用本文:李清华,程绍忠,孙淑云. 文拉法辛与阿米替林治疗抑郁症对照研究[J]. 中国民康医学, 2008, 20(5): 398-399
作者姓名:李清华  程绍忠  孙淑云
作者单位:烟台市心理康复医院,山东,烟台,265200
摘    要:目的:探讨文拉法辛的抗抑郁疗效及安全性。方法:采用随机对照方法,两组分别给予文拉法辛和阿米替林,采用HAMD,HAMA,TESS评定疗效及不良反应。结果:文拉法辛组显效率为87%,阿米替林组为81%,两组间比较无显著性差异(P>0.05),但文拉法辛起效较快,且不良反应少。结论:文拉法辛疗效肯定,不良反应少,安全性高。

关 键 词:文拉法辛  阿米替林  抑郁症

A Comparative Study of Venlafaxine and Amitriptyline in the treatment of Depressive Disorder
LI Qing-hua,GHENG Shao-zhong,SUN Shu-yun. A Comparative Study of Venlafaxine and Amitriptyline in the treatment of Depressive Disorder[J]. medical journal of chinese peoples health, 2008, 20(5): 398-399
Authors:LI Qing-hua  GHENG Shao-zhong  SUN Shu-yun
Abstract:Objective:To explore the clinical effect and safety of Venlafaxine in the treatment of the depression disorder. Methods:The patients were divided into two groups randomly and took Venlafaxine or Amitriptyline. Rating them by HAMD, HAMA and TESS scale.Results: 87% patients in Venlafaxine group and 81% in Amitriptyline group had obtained clinical effect. There was no significant deference between two groups (P<0.05). But it was faster to work and had fewer side effects in Venlafaxine group than that in Amitriptyline group.Conclusions: Venlafaxine has affirmative clinical effect, little side effect and high safety in treating depression disorder.
Keywords:Venlafaxine  Amitriptyline  Depression disorder
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