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Celiac Disease Diagnosed after Gastrectomy for Gastric Cancer
Authors:Maho Iwamoto  Kimitoshi Kato  Yoshiaki Kusumi  Shinobu Masuda  Tomohiro Nakayama  Mitsuhiko Moriyama
Affiliation:1.Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nihon University School of Medicine, Japan; 2.Division of Research Planning and Development, Nihon University School of Medicine, Japan; 3.Department of Pathology, Nihon University School of Medicine, Japan; 4.Division of Laboratory Medicine, Department of Pathology and Microbiology, Nihon University School of Medicine, Japan
Abstract:
Celiac disease is a systemic autoimmune disorder leading to manifestations of malabsorption syndrome. A 47-year-old Japanese man developed severe diarrhea after surgery for gastric cancer. The diarrhea persisted for seven months, leading to a state of malabsorption. Celiac disease was suspected based on small bowel capsule endoscopy findings. The duodenal findings observed during gastric cancer surgery were reassessed, and Marsh-Oberhuber classification type 3c celiac disease was diagnosed. The anti-tissue glutaminase antibody test results were positive. The patient was started on a gluten-free diet, following which the diarrhea resolved, and the nutritional status improved. Adjuvant therapy after gastric cancer surgery was initiated.
Keywords:celiac disease   gastric cancer   post-gastrectomy   small bowel capsule endoscopy   diarrhea
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