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NT—proBNP床旁检测在急性冠脉综合征中的应用
引用本文:陈牧雷,徐立,于丽萍,李奎宝,孙昊,赵晓涛,李强,张海泳,王红,杨新春. NT—proBNP床旁检测在急性冠脉综合征中的应用[J]. 中国病案, 2010, 11(2): 21-23
作者姓名:陈牧雷  徐立  于丽萍  李奎宝  孙昊  赵晓涛  李强  张海泳  王红  杨新春
作者单位:首都医科大学附属北京朝阳医院心脏中心,北京市,100020
摘    要:目的探讨急性冠脉综合征(ACS)患者,入院即刻床旁检测(POCT)N末端B型钠尿肽原(NT-proBNP)的I临床应用价值。方法应用加拿大Respense Biomedical公司RAMP(r)(锐普)荧光干式定量分析仪,检测63例ACS患者血中NT-proBNP的水平,分析其与年龄、临床心功能分级、B超左室射血分数(LVEF)以及住CCU时间、住院时间之间的关系。结果血液NT-proBNP测值〈125ng/L与≥125ng/L组比较,前者平均年龄较小(55±10,4岁VS69.7±10.5岁,P〈0.05),LVEF值较高(63.1%±8.O%VS56.8%±13.5%,P〈0.05),平均住CCU时间较短(3.3±1.1天VS4.7±3.8天,P〈0.05),平均住院时间也较短(9.8±3.0天VS14.6±10.1天,P〈0.05)。结论人院即刻以POCT法测定血中NT-proBNP水平,有助于ACS患者疾病严重程度的判断,为临床诊疗提供依据。

关 键 词:急性冠脉综合征  N末端B型钠尿肽原  床旁检测  心脏功能

The value of point of care testing of N-terminal-pro-B-type natriuretic peptidein acute coronary syndrome
Chen Mulei,Xu Li,Yu Liping,Li Kuibao,Sun Hao,Zhao Xiaotao,Li Qiang,Zhang Haiyong,Wang Hong,Yang Xinchun. The value of point of care testing of N-terminal-pro-B-type natriuretic peptidein acute coronary syndrome[J]. Chinese Medical Record, 2010, 11(2): 21-23
Authors:Chen Mulei  Xu Li  Yu Liping  Li Kuibao  Sun Hao  Zhao Xiaotao  Li Qiang  Zhang Haiyong  Wang Hong  Yang Xinchun
Affiliation:Chen Mulei,Xu Li,Yu Liping,Li Kuibao,Sun Hao,Zhao Xiaotao,Li Qiang,Zhang Haiyong,Wang Hong,Yang Xinchun.Institute of Cardialvascular Disease,Heart Center of Beijing Chaoyang Hospital,Affiliated to Capital University of Medical Science,Beijing,100020
Abstract:Objective To assess the value of N-terminal pro-B-type natriuretic peptide(NT-pro-BNP)measured by point of care testing(POCT)in acute coronary syndrome(ACS)patients on admission.Methods Blood levels of NT-pro-BNP of 63 ACS patients were tested by the Canadian POCT Response Biomedical RAMP NT-proBNP assay.The relationship between the testing results and age,heart function,left ventricular ejection function(LVEF),days stayed in cardiac care unit(CCU)and days stayed in hospital was analysed.Results The patient...
Keywords:acute coronary syndrome(ACS)  N-terminal pro-B-type natriuretic peptide(NT-pro-BNP)  point of care testing(POCT)  heart function  
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