2006—2015年度国家自然科学基金“肿瘤放疗”领域项目资助情况及分析

目的 介绍2006—2015年度“肿瘤放疗”领域国家自然科学基金项目申请及资助情况。方法 在ISIS系统中通过学科代码(H1610)和“肿瘤放疗”关键词检索2006—2015年国家自然科学基金在“肿瘤放疗”领域的资助信息，分析项目的研究领域分布、申请人及依托单位的地域分布、单位性质等。结果 近10年肿瘤放疗领域资助项目共435项，资助金额1.8亿元，数量和金额均呈逐年递增趋势。面上、青年和地区基金占资助数量和强度比例最大，单项资助金额分别为53、22、40万。资助项目依托单位较为集中，申请量在前十名的单位获得资助项目数的53%。基础机制类研究占资助总数88%，涵盖放疗生物学效应、微环境、干细胞等肿瘤学前沿及热点，少数研究侧重于物理(12%)。资助项目数和经费前3位的肿瘤为肺癌、鼻咽癌和食管癌。结论 10年来肿瘤放疗领域项目资助数呈上升势头，资助金额稳步增加;研究队伍区域分布明显，东部地区研究实力突出;机制类研究中的放疗生物学效应相关研究最为普遍。

An analysis of projects in radiation oncology funded by National Natural Science Foundation of China from 2006 to 2015

Objective To analyze the application and funding for projects in radiation oncology from National Natural Science Foundation of China (NNSFC) from 2006 to 2015. Methods To collect the funding information in radiation oncology from NNSFC from 2006 to 2015, a computerized search was performed in the ISIS system using a subject code of H1610 and a keyword of radiation oncology. Analyses were performed in distribution of research fields, the geographical distribution of applicants, and the properties of institutes/universities the applicants were affiliated with. Results In the last decade, a total of 435 projects in the field of radiation oncology were funded with 180 million yuan. Most projects were funded by general, youth, and regional foundation, which covered the highest proportion of NNSFC. For a single project, the amounts of funding from general, youth, and regional foundations were 530, 220, and 400 thousand yuan, respectively. The institutes/universities the NNSFC-funded projects were affiliated with were located quite close to each other. The top 10 institutes/universities in terms of the number of NNSFC-funded projects covered 53% of projects. In all projects, 88% studied basic science, which covered many hot topics in oncology including biological effects of radiotherapy, microenvironment, and stem cells. A small number (12%) of projects focused on physics. Top 3 cancers in terms of the number of projects and the amount of funding were lung cancer, nasopharyngeal carcinoma, and esophagus cancer. Conclusions In the last decade, the field of radiation oncology has stable increases in the number of NNSFC-funded projects and the amount of funding. The NNSFC-funded research teams are unevenly distributed, most of which are located in East China. The most popular topic in basic science studies is about biological effects of radiotherapy.