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宫颈锥切术后HPV检测的临床意义
引用本文:郝凤英,魏力.宫颈锥切术后HPV检测的临床意义[J].现代肿瘤医学,2011,19(4):752-754.
作者姓名:郝凤英  魏力
作者单位:中国医科大学附属第四医院妇科,辽宁,沈阳,110032
基金项目:辽宁省教育厅高等学校科研项目计划(A类)
摘    要:目的:探讨人乳头瘤病毒(HPV)在宫颈上皮内瘤样病变(CIN)行LEEP、冷刀锥切(CKC)术后的随访价值。方法:回顾分析180例行LEEP锥切、119例行冷刀锥切的CIN患者术前、术后HPV感染情况,观察锥切术后CIN的消失情况。结果:二者手术前后HPV感染率分别为:LEEP组78.3%和7.8%,CKC组64.7%和6.7%,无统计学差异,术后HPV感染率明显降低,术后HPV持续感染者宫颈病变进展率高于HPV转阴者,二者有统计学差异。结论:HPV检测在LE EP、CKC术后可作为随访有效手段。

关 键 词:宫颈上皮内瘤样病变  宫颈锥切术  人乳头瘤病毒

Clinical significance of HPV test in CIN after conization of cervix
HAO Feng-ying,WEI Li.Clinical significance of HPV test in CIN after conization of cervix[J].Journal of Modern Oncology,2011,19(4):752-754.
Authors:HAO Feng-ying  WEI Li
Institution:Departerment of Gynecology,the Forth Affliated Hospital of China Medical Uiversity.Shenyang 110032,China.
Abstract:Objective:To explore the significance of HPV infection in CIN after surgical cone of LEEP and cold-knife conization(CKC).Methods:Total of 180 patients with LEEP 119 patients with CKC were analyzed retrospectively.Pre-and post-conization HPV infection was tested respectively.Results:The rate of HPV infection in women Pre-and post-conization with LEEP and CKC was 78.3% and 7.8%,64.7% and 6.7% respectively.There was no statistical significant defference.The rate of HPV infection in women of post-conization decreased progressively Recurrence of CIN after surgery is higher in those of HPV infection than those of uninfection.Conclusion:HPV test is a useful method for clinical evaluation of patients after cervical coniztionin with LEEP and CKC.
Keywords:CIN  conization  HPV
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