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Endovascular papillary angioendothelioma (Dabska tumor) in an elderly woman
Authors:Akihiko Yamada  Kunio Uematsu  Hitoshi Yasoshima  Kazunari Sakurai  Kazutoshi Hori  Munehlko Ohya  Eriko Ohkubo  Hiroshi Ogasawara
Affiliation:Department of Pathology (Hospital), Hyogo College of Medicine, Nishinomiya, Japan;Second Department of Pathology, Hyogo College of Medicine, Nishinomiya, Japan;Department of Otolaryngology, Hyogo College of Medicine, Nishinomiya, Japan
Abstract:
A patient with endovascular papillary angioendothelioma with a low grade of malignancy showing papillary proliferation of endothellold cells Is presented. The patient, an 83-year-old woman, underwent resection of a tumor of the neck. At operation a 9×7 cm cystic tumor containing yellow transparent liquid with clots was found In the subcutaneous tissue. Histological studies showed endotheliold cells with spindle-shaped nuclei proliferated in layers around the fibrovascular cores, which showed the characteristic appearance of papillary proliferation. These cells were Immunohlstochemlcally positive for CD31, CD34 and factor VIII-related antigen. Based on these observations, the tumor was considered to be an endovascular papillary angioendothelioma (Dabska tumor). Dabska tumor Is a vascular tumor with a low grade of malignancy and usually occurs in infants and young children. About 13 cases of Dabska tumor have been reported. The occurrence of a Dabska tumor In an aged patient is considered to be rare.
Keywords:Dabska tumor    endovascular papillary angioendothelioma    hemangioendothelioma
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