丙泊酚复合瑞芬太尼用于人工流产术的麻醉

目的:观察丙泊酚复合瑞芬太尼用于人工流产术的麻醉效果及对呼吸、循环系统的影响。方法:选择40例拟行人工流产术且无相关禁忌证的患者,ASAⅠ~Ⅱ级,年龄18~32岁,体重43kg~62kg。随机分为两组,丙泊酚复合瑞芬太尼组(R组)和丙泊酚组(P组),每组各20例。两组手术方法相同,年龄、体重和人流时间均无差异(P>0.05)。R组瑞芬太尼静脉滴注剂量为0.75μg/kg,丙泊酚静脉滴注剂量为2mg/kg,P组丙泊酚静脉滴注剂量为3mg/kg。两组待麻醉满意后开始行人工流产术,同时观察诱导前、诱导后、手术结束时血压(Bp)、心率(HR)、血氧饱和度(SpO2)以及苏醒时间,并对麻醉效果进行分析评价。结果:R组诱导和苏醒时间明显短于P组(P<0.05);P组诱导后2min时Bp下降、HR减慢、SpO2降低比R组明显(P<0.05);R组麻醉效果明显优于P组(P<0.05)。结论:丙泊酚复合瑞芬太尼用于人工流产,麻醉镇痛效果确切,用药量小,起效快,呼吸、循环抑制较轻,患者术后苏醒快,此方法优于单纯用丙泊酚麻醉治疗者。

Anesthesia with Propofol combined with remifentanil in artificial abortion

Objective To investigate the anesthesia effect of Propofol combined with remifentanil in artificial abortion and the possible impact on respiratory system and circulation system.Method Forty patients undergoing artificial abortion(ASA I～II,age: 18～32 years,weight: 43～62kg) were allocated into two groups randomly as Propofol combined with remifentanil group(group R) and Propofol group(group P),with 20 patients in each group.Group R was administered Propofol(2mg/kg,i.v.) combined with remifentanil(0.75μg/㎏,i.v.) and group P was administered Propofol(3mg/kg,i.v.).The two groups received the same operation with the same method,and there was no significant meaning of age,weight and abortion time between the two groups(P>0.05).Blood pressure(BP),heart rate(HR),saturation of blood oxygen(SpO2),awake time and anesthesia effect were observed pre-anesthesia,post-anesthesia and end of anesthesia,respectively.Results Induction time and awake time of group R were significantly shorter than that of group P(P<0.05);The decrease of BP,HR and SpO2 in group P 2min after anesthesia were more obvious than that of group R(P<0.05).The anesthesia effect in group R was better than that of group P(P<0.05).Conclusion Anesthesia with Propofol plus remifentanil in artificial abortion has a definite effect of analgesia.Little dosage,working and waking fast,little inhibition in respiritory and circulation system make it better than anesthesia with Propofol alone.