| 甾体激素受体PR、ER表达与子宫内膜癌淋巴结转移关系的研究 |
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| 引用本文： | 陈雅卿,楼洪坤. 甾体激素受体PR、ER表达与子宫内膜癌淋巴结转移关系的研究[J]. 中华肿瘤防治杂志, 2002, 9(5): 478-479 |
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| 作者姓名： | 陈雅卿 楼洪坤 |
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| 作者单位： | 浙江肿瘤医院妇科,浙江,杭州,310022;浙江肿瘤医院妇科,浙江,杭州,310022 |
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| 摘 要： | 目的 :探讨激素受体PR、ER表达与子宫内膜癌淋巴结转移的关系。方法 :采用免疫组化法对15 9例子宫内膜组织中的PR、ER表达进行检测。结果 :PR阴性子宫内膜癌的淋巴结阳性率明显高于PR阳性者 ,两者差异有显著性 (P <0 0 1) ;ER阳性和阴性的淋巴结阳性率差异无显著性 (P >0 0 5 ) ;PR、ER阴性表达的淋巴结阳性率为 5 1 5 % ,而PR、ER阳性者为 10 7% ,两者差异有极显著性 (P <0 0 1)。结论 :PR表达与子宫内膜癌的淋巴结转移更具相关性 ,可将PR、ER表达结果作为评估盆腔淋巴结转移的参考指标之一
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| 关 键 词： | 子宫内膜肿瘤 雌激素/分析 受体 孕酮/分析 免疫组织化学 |
| 文章编号： | 1009-4571(2002)05-0478-02 |
| 修稿时间： | 2002-01-31 |
Correlation with Expression of PR/ER and Lymph Node Metastases in Endometrial Carcinoma |
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| CHEN Ya-qing,LOU Hong-kun.Zhejiang Tumor Hospital,Hangzhou ,China. Correlation with Expression of PR/ER and Lymph Node Metastases in Endometrial Carcinoma[J]. Chinese Journal of Cancer Prevention and Treatment, 2002, 9(5): 478-479 |
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| Authors: | CHEN Ya-qing LOU Hong-kun.Zhejiang Tumor Hospital Hangzhou China |
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| Affiliation: | CHEN Ya-qing,LOU Hong-kun.Zhejiang Tumor Hospital,Hangzhou 310022,China |
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| Abstract: | Objective To Study the relationship between expression of PR/ER and lymph node metastases in endometrial carcinoma.Methods To detect PR and ER expression in 159 patients with endometrial carcinoma by means of immumohisnochemistry.Results Lymph node metastases from endometrial carcinoma were statistically correlated with negative expression of PR, no Correlation existed between ER expression and lymph node metastases.Conclusions In endometrial carcinoma,PR expression was highly related to the lymph node metastases, PR and ER expression might be a available prognostic factor associated with lymph node metastases. |
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| Keywords: | endometrial neoplasms estrogens/analysis receptors progesterone/analysis immunohistochemistry |
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