恩施藤茶对高脂血症大鼠血脂代谢的影响

目的探讨藤茶饮用对高脂血症的预防保健作用.方法将Wistar大鼠30只随机等分为对照组、高脂血症模型组(以下简称模型组)和藤茶组.根据实验要求,分别按标准喂养15周后测定每组动物个体血脂、血液流变和氧自由基的变化.结果与对照组比较,模型组胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)升高,脂质过氧化物(MDA)含量增加,超氧化物岐化酶(SOD)及谷光甘肽过氧化物酶(GSH-PX)活性明显降低,血液流变学异常改变;与模型组比较,藤茶组动物血浆中TC、TG值明显降低,高密度脂蛋白(HDL-C)升高, MDA含量减少,SOD及GSH-PX活性增强,血液黏度、红细胞和血小板聚集能力明显降低.结论长期饮用藤茶能够调节血脂代谢、改善血流状态、清除氧自由基,对高脂血症一定的预防保健作用.

Effects of Enshi-Ampelopsis Grossede on Serum Lipid and Blood Rheology and Oxygen Free Radical of Hyperlipidemia Model Rats

Objective To study the preventive and health effects of enshi-ampelopsis grossede on hyperlipidemia.Methods 30 wistar rats were divided into three groups:control group,model group and ampelopsis grossede group.wistar rats were fed respectively with standard diet,15 weeks later,to measure serum lipid,blood rheology and oxygen free radical in rats.Result At the end of experiment,the serum TC,TG and LDL-C levels of model groups were higher than that of control groups,the quality of MDA were higher,the activity of SOD and GSH-PX were lower,blood rheology were significantly changed.the serum TC and TG levels of ampelopsis grossede groups were significantly lower than that of model groups,HDL-C was higher,the quality of MDA were lower,the activities of SOD and GSH-PX were higher,blood viscosity,the ability of RBC and platelet aggregation were significantly lower.Conclusion Constant drinking of ampelopsis grossede can regulate hyperlipidemia rats serum lipid and lipoprotein,improve hermorrheology,clean oxygen free radical,there were preventive and health effects of enshi-ampelopsis grossede on hyperlipidemia and cardiovascular disease.