| RAB5A对人肺腺癌细胞系粘附能力的影响 |
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| 引用本文： | 王春梅,卜晓波,韩彦龙,董凯. RAB5A对人肺腺癌细胞系粘附能力的影响[J]. 牡丹江医学院学报, 2001, 22(2): 5-6 |
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| 作者姓名： | 王春梅 卜晓波 韩彦龙 董凯 |
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| 作者单位： | 牡丹江医学院,生物教研室;牡丹江医学院,生物教研室;牡丹江医学院,生物教研室;牡丹江医学院,生物教研室 |
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| 摘 要： | 目的：研究RAB5A基因转染后对肺腺癌粘附能力的影响。方法：采用细胞粘附能力测定,观察转染前后细胞系粘附能力的改变。结果：转染PAB5A正义表达载体的AG2Y83－α细胞系粘附能力增强,转染反义重组质粒的Anip9n3细胞系粘附能力明显减弱。结论：RAB5A在人肺腺癌转移特性的形成中具有重要的作用。
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| 关 键 词： | RAB5A 肿瘤转移 粘附能力 |
| 修稿时间： | 2000-06-06 |
THE ETFECT OF RAB5A ON ADHESION CAPABILIY OF HUMAN LUNG ADENOCARCINOMA CELL LINES |
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| Wang chunmei et al Biology Depantment of Mu DanJiang Medical college. THE ETFECT OF RAB5A ON ADHESION CAPABILIY OF HUMAN LUNG ADENOCARCINOMA CELL LINES[J]. Journal of Mudanjiang Medical College, 2001, 22(2): 5-6 |
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| Authors: | Wang chunmei et al Biology Depantment of Mu DanJiang Medical college |
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| Affiliation: | Wang chunmei et al Biology Depantment of Mu DanJiang Medical college 157011 |
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| Abstract: | object:to investigate the effect of RAB5A gene on forminy of tumor metastatic natuke.Method:usel adehesion capability of tumor cell assay.Results:the resluts suggest that metastatic capability of AGZY83-9 cells of tran sfected RAB5A was higher than parent line,and Anip973 cells of transfccted Anti RAB5A was lower than Anip973 cells.Conclusion:our research in vitro indicate that RAB5A gene over-expression plays im portant role in tumor invasion phenotype formation metastatic Rature of human lung adenocar cinoma cells. |
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| Keywords: | RAB5A metastatic of tumor adehesion. |
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