| 槟榔化学成分研究 |
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| 作者姓名： | Yang WQ Wang HC Wang WJ Wang Y Zhang XQ Ye WC |
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| 作者单位： | 暨南大学药学院中药及天然药物研究所/暨南大学中药药效物质基础及创新药物研究广东省高校重点实验室;青岛市市立医院 |
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| 基金项目： | 教育部长江学者创新团队项目(IRT0965);广东省自然科学基金团队项目(8351063201000003) |
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| 摘 要： | 目的:研究槟榔种子的化学成分。方法:采用硅胶柱、反相RP-18柱、Sephadex LH-20柱等色谱方法进行分离纯化,根据理化性质与波谱数据鉴定化合物结构。结果:分离鉴定了13个化合物,分别为:异鼠李素(1)、槲皮素(2)、甘草素(3)、5,7,4'-trihydroxy-3',5'-dimethoxyflavanone(4)、(+)-儿茶素(5)、反式白黎芦醇(6)、阿魏酸(7)、香草酸(8)、过氧麦角甾醇(9)、豆甾-4-烯-3-酮(10)、β-谷甾醇(11)、环阿尔廷醇(12)、de-O-methyllasiodiplodin(13)。结论:其中,化合物2～4、6、7、9、10、12、13为首次从该植物中分离得到。
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| 关 键 词： | 槟榔 化学成分 |
Chemical constituents from the fruits of Areca catechu |
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| Yang WQ,Wang HC,Wang WJ,Wang Y,Zhang XQ,Ye WC.Chemical constituents from the fruits of Areca catechu[J].Jorunal of Chinese Medicinal Materials,2012,35(3):400-403. |
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| Authors: | Yang Wen-Qiang Wang Hong-Cheng Wang Wen-Jing Wang Ying Zhang Xiao-Qi Ye Wen-Cai |
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| Institution: | Institute of Traditional Chinese Medicine & Natural Products,Jinan University /Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research,Jinan University, Guangzhou 510632, China. |
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| Abstract: | Objective: To investigate the chemical constituents of the fruits of Areca catechu.Methods: The chemical constituents were isolated by silica gel,RP-18 and Sephadex LH-20 column chromatographies.Their structures were determined by chemical and spectroscopic methods.Results: Thirteen compounds were isolated from the 95% ethanol extract of the fruits of Areca catechu.Their structures were identified as isorhamnetin(1),quercetin(2),liquiritigenin(3),5,7,4′-trihydroxy-3′,5′-dimethoxyflavanone(4),(+)-catechin(5),resveratrol(6),ferulic acid(7),vanillic acid(8),5,8-epidioxiergosta-6,22-dien-3β-ol(9),stigmasta-4-en-3-one(10),β-sitosterol(11),cycloartenol(12),and deO-methyllasiodiplodin(13),respectively.Conclusion: Compounds 2~4,6,7,9,10,12,13 are isolated from this plant for the first time. |
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| Keywords: | Areca catechu L Chemical constituents |
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