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Th17细胞及其分泌的IL-17在自身免疫性溶血性贫血患者中的变化及意义
引用本文:He HS,Xie YH. Th17细胞及其分泌的IL-17在自身免疫性溶血性贫血患者中的变化及意义[J]. 细胞与分子免疫学杂志, 2011, 27(6): 662-663
作者姓名:He HS  Xie YH
作者单位:1. 皖南医学院附属弋矶山医院血液科,安徽,芜湖,241001
2. 复大学附属华山医院血液科,上海,200040
基金项目:上海市科学和技术委员会生物医药重大攻关课题专项研究基金资助项目
摘    要:
目的:观察辅助性17 T细胞(Th17)及其分泌的细胞因子IL-17在自身免疫性溶血性贫血(AIHA)患者中的变化并探讨其临床意义.方法:应用流式细胞术(FCM)检测治疗前与糖皮质激素治疗后AIHA患者和健康人外周血中Th17细胞的比率,同时用ELISA法检测血浆中IL-17的水平.结果:治疗前AIHA患者外周血中Th...

关 键 词:Th17细胞  IL-17  自身免疫性,溶血性,贫血

Change and significance of Th17 cells and its secretive IL-17 in patients with autoimmune hemolytic anemia
He He-sheng,Xie Yan-hui. Change and significance of Th17 cells and its secretive IL-17 in patients with autoimmune hemolytic anemia[J]. Chinese journal of cellular and molecular immunology, 2011, 27(6): 662-663
Authors:He He-sheng  Xie Yan-hui
Affiliation:HE He-sheng1,XIE Yan-hui21Department of Hematology,Yijishan Hospital,Wannan Medical College,Wuhu 241001,2Department of Haematology,Huashan Hospital,Affiliated to Fudan University,Shanghai 200040,China
Abstract:
AIM: To observe the percentage of Th17 cells in the peripheral blood and levels of plasma IL-17 of patients with autoimmune hemolytic anemia(AIHA)before treatment and after glucocorticoid treatment and to explore their clinical significance.METHODS: Flow cytometric assay were used to detect the rate of Th17 cells in AIHA patients.The level of plasma IL-17 in AIHA patients were measured by ELISA.RESULTS: The rate of Th17 cells and the level of plasma IL-17 were significantly increased before treatment as com...
Keywords:IL-17
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