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强直性脊柱炎患者血清HVEM和IL-17含量测定及意义
引用本文:黄碧,曾今诚,张俊爱,向文玉,曹传勇. 强直性脊柱炎患者血清HVEM和IL-17含量测定及意义[J]. 医学检验与临床, 2013, 0(3): 9-11
作者姓名:黄碧  曾今诚  张俊爱  向文玉  曹传勇
作者单位:1. 湛江市结核病防治所检验科,广东湛江,524008
2. 广东医学院检验医学研究所,广东,523808
3. 广东医学院附属医院检验科,广东,524001
摘    要:目的:检测强直性脊柱炎(AS)患者血清中可溶性HVEM和IL-17含量并探讨其临床意义。方法:ELISA检测33例AS患者和42例健康自愿者血清可溶性HVEM和IL-17含量。结果:AS患者血清可溶性HVEM含量为(102.8±69.4)肛g/L,健康自愿者血清可溶性HVEM为(53.5±24.1)恤g/L,两者比较差异有统计学意义(P〈0.05)。强直性脊柱炎患者血清IL-17含量(267.31±53.50)pg/ml明显高于健康对照组(201.43±47.52)pg/ml,差异有统计学意义(P〈0.05)。结论:检测血清HVEM和IL-17水平对As的辅助诊断及疗效评估有一定的参考价值。

关 键 词:强直性脊柱炎HVEM  IL-17  ELISA

The determination and significance of serum HVEM and IL-17 content in patients with Ankylosing Spondylitis
HUANG Bi , ZENG Jin-cheng , ZHANG Jun-ai , XIANG Wen-yu , CAO Chuan-yong. The determination and significance of serum HVEM and IL-17 content in patients with Ankylosing Spondylitis[J]. Medical Laboratory Science and, 2013, 0(3): 9-11
Authors:HUANG Bi    ZENG Jin-cheng    ZHANG Jun-ai    XIANG Wen-yu    CAO Chuan-yong
Affiliation:3 (Tuberculosis Dispensary of Zhanjiang, Zhanjiang 524008,China)
Abstract:Objective : To research the clinical significance of the level of serum HVEM and IL-17 in patients with ankylosing spondylitis (AS). Methods : Serum HVEM and IL-17 levels were determined in 33 patients with AS and in 42 controls by ELISA. Results : The serum HVEM levels in patients with AS ( 102.8 ± 69.4 ) μ g/L were significantly higher than those in healthy controls ( 53.5± 24.1 ) μ g/L, P〈0.05. The serum IL-17 levels in patients with AS ( 267.31 ± 53.50 ) pg/m L were significantly higher than those in healthy controls ( 201.43 ± 47.52 ) pg/m L, P〈0.05 .Conclusions : Serum HVEM and IL-17 levels provided a useful information for diagnosis and evaluation of AS.
Keywords:Ankylosing Spondylitis  HVEM  IL-17  ELISA
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