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| Expressions of Substance P in Trigeminal Ganglia in Rats with Occlusal Reconstruction | |
| 引用本文： | LI Xiao-guang ZHU Sheng-rong XIAO Chang-jie WANG Yan-xiu. Expressions of Substance P in Trigeminal Ganglia in Rats with Occlusal Reconstruction[J]. 美中医学, 2008, 5(1): 13-16 |
| 作者姓名： | LI Xiao-guang ZHU Sheng-rong XIAO Chang-jie WANG Yan-xiu |
| 作者单位： | [1]Department of Stomatology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030 [2]Department of Stomatology, Tai＇an City Central Hospital, Tai ＂an 271000 [3]Department of Anesthesiology, Tai＇an City Central Hospital, Tai＇an 271000 |
| 基金项目： | Acknowledgements： This work was supported by a grant from the Tai＇an City Science and Technique Bureau （No. 2003-52）. |
| 摘 要： | Objective To study the expressions of substance P （SP） in trigeminal ganglia （TG） in rats with occlusal reconstruction. Methods 30 Wistar male rats were randomly divided into 3 experimental groups and 3 control groups, 5 rats in each group. The molar of right maxillary and mandibular of rats in experimental groups were ground to the gingival level without occlusal contact. The occlusal contact was recovered by stopping grounding molar of the rats. The section of trigeminal ganglia underwent the immunohistological study to evaluate the expressions of SP by using SABC method. Light microscope and microscoic photo analytic software were employed to detect the percentage of SP positive neurons in frozen section of TG in 30 rats. SPSS10.0 statistical software was used for statistical analysis. Results There was no significantly difference in the percentage of SP positive neurons between the early occlusal reconstruction experiment group and control group （P〉0.05）. There was significantly difference in the percentage of SP positive neurons between the later occlusal reconstruction experiment group and control group （P〈0.01, P〈0.05）. Conclusion The expressions of SP in TG can recover normal in the early occlusal reconstruction and that not in the later occlusal reconstruction. SP might participate in the histopathologic mechanism of temporomandibular disorders. |
| 关 键 词： | 三叉神经 咬合面重建 P物质 鼠 表达 口腔颌面 |
Expressions of Substance P in Trigeminal Ganglia in Rats with Occlusal Reconstruction |
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| LI Xiao-guang,;ZHU Sheng-rong,;XIAO Chang-jie,;WANG Yan-xiu. Expressions of Substance P in Trigeminal Ganglia in Rats with Occlusal Reconstruction[J]. Journal of US-China Medical Science, 2008, 5(1): 13-16 | |
| Authors: | LI Xiao-guang, ZHU Sheng-rong, XIAO Chang-jie, WANG Yan-xiu |
| Abstract: | substance P trigeminal ganglia occlusal reconstruction rats |
| Keywords: | substance P trigeminal ganglia occlusal reconstruction rats |
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