| 参麦注射液对大鼠心肌缺血/再灌注心律失常的影响 |
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| 引用本文： | 姬克. 参麦注射液对大鼠心肌缺血/再灌注心律失常的影响[J]. 中国现代医药杂志, 2011, 13(2) |
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| 作者姓名： | 姬克 |
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| 作者单位： | 河南省驻马店市汝南县人民医院,463300 |
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| 摘 要： | 目的 探讨参麦注射液对大鼠缺血/再灌注心律失常的影响及其作用机制.方法 复制大鼠缺血/再灌注模型,采用缺血10min和缺血60min两种模型观察缺血性心律失常,观察发生率最高的缺血10min后再灌注心律失常,对照组和参麦注射液组分别给予生理盐水和参麦注射液1.5ml/kg,动态Ⅱ导心电图监测室性早搏(PVB)、室性心动过速(VT)及心室颤动与扑动(VF)的发生率.结果 参麦注射液可明显减少缺血10min和60min心律失常PVB、VT、VF的发生率(P＜0.01),亦可明显减少再灌注10min心律失常VT(P＜0.05)及VF(P＜0.01)的发生率.结论 参麦注射液可明显减少大鼠缺血/再灌注心律失常的发生率.
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| 关 键 词： | 心肌再灌注损伤 大鼠 心律失常 |
Effect of Shenmai injection on arrhyth mia in rats with myocardial ischemia reperfusion injury |
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| Ji Ke. Effect of Shenmai injection on arrhyth mia in rats with myocardial ischemia reperfusion injury[J]. Modern Medicine Journal of China, 2011, 13(2) |
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| Authors: | Ji Ke |
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| Affiliation: | Ji Ke. The People's Hospital of Runan,Zhumadian 463300 |
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| Abstract: | Objective To investigate the effect and mechanism of Shenmai injection on arrhythmia in rats with myocardial ischemia/reperfusion injury. Methods Reproducing myocardial ischemia/reperfusion injury model of rats, observe ischemia arrhythmia after 10, 60 minutes and reperfusion arrhythmia after 10 minutes. 1.5ml/kg 0.9% NaCl and Shenmai injection were given control and Shenmai groups respectively before supervise occurrence ratio of premature ventricular beats(PVB), ventricular tachycardia(VT), ventricular fi... |
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| Keywords: | Myocardial reperfusion injury Rat Arrhythmia |
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