双源CT冠状动脉造影对老年与中年冠状动脉狭窄的评价作用研究

抽取我院行双源CT冠状动脉造影（DSCTA）检查确诊为冠心病的100例患者分成老年组53例和中年组47例。DSCTA使用曲面重建和最大密度投影等后处理重建技术，以冠状动脉X线造影检查结果为标准，在段的基础上评价冠脉狭窄程度≥50％的各项指标及差异。结果显示，DSCTA对老年组和中年组冠状动脉的可评价率分别为97．0％、98．6％，两组比较差异无统计学意义（P〉0．05）。老年组和中年组冠状动脉狭窄≥50％节段发生率分别为12．6％、9．0％，多支血管病变发生率分别为28．3％、6．4％，两组比较差异均有统计学意义（P〈0．05）。DSCTA评价老年组冠状动脉狭窄程度〉150％的敏感度、特异度、阳性预测值、阴性预测值依次为92．3％、98．0％、88．0％、98．9％；评价中年组的各项指标依次为96．0％、99．0％、90．6％、99．6％；两组比较差异无统计学意义（P〉0．05）。提示，DSCTA可作为冠心病的有效筛查和评价方法；评价冠状动脉狭窄的各项指标随着年龄增长有下降趋势，但差异无统计学意义。

Dual-source CT angiography for evaluation of coronary artery stenosis in elderly and middle-agedpatients

One hundred patients were diagnosed with coronary heart disease through dual-source CT coronary angiography (DSCTA) in our hospital,including 53 cases aged ≥60 y (elderly group) and 47 cases ＜60 y (middle-aged group).The curved-planar reconstruction (CPR),maximal intensity projection (MIP) and other post-processing reconstruction techniques were used to evaluate the indicators and differences of coronary stenosis ≥ 50％ ; the X-ray coronary angiography (CAG) findings were regarded as the gold standard.The evaluable rates of coronary arteries through DSCTA were 97.0％ and 98.6％ for two groups (P ＞0.05).The positive rate of coronary artery stenosis ≥ 50％ in elderly group was higher than that of middle-age group ( 12.6％ vs 9.0％ P ＜0.05 ).The rates of multi-vessel disease in elderly group (28.3％ ) was also significantly higher than that of middle-age group (6.4％,P ＜0.05 ).The sensitivity,specificity,positive predictive value and negative predictive value in evaluation of coronary artery stenosis ≥ 50％ for elderly patients were 92.3％,98.0％,88.0％ and 98.9％ respectively; those for middle-aged patients were 96.0％,99.0％,90.6％ and 99.6％ respectively ( P ＞0.05 ).DSCTA imaging provides an effective screening and evaluation method for coronary heart disease in elderly and middle-aged patients.