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射频消融联合肝动脉化疗栓塞对原发性肝癌的疗效分析
引用本文:宋莉,佟小强,王健,杨敏,吕永兴,邹英华.射频消融联合肝动脉化疗栓塞对原发性肝癌的疗效分析[J].当代医学,2009,15(23):404-406.
作者姓名:宋莉  佟小强  王健  杨敏  吕永兴  邹英华
作者单位:北京,100034,北京大学第一医院介入血管外科
摘    要:目的评价射频消融联合肝动脉化疗栓塞对原发性肝癌的治疗效果,总结治疗过程中的经验教训。方法对81例原发性肝癌患者共114个病灶进行射频消融治疗联合肝动脉化疗栓塞。术前术后患者均进行增强CT扫描,随访期间患者每2~3个月进行一次CT扫描。结果平均随访30±10.9(17~49)个月。至观察终点1、2、3年生存率分别为96.6%、93.2%和68.2%。中位生存期为34个月(95%CI:18~49月)。全组死亡24例,目前存活57例,其中35例处于疾病控制期。结论射频消融结合TACE治疗可有效治疗原发性肝癌,可延长患者的生存期。

关 键 词:射频消融  肝脏恶性肿瘤

Effect of RFA combined with TACE for Primary Hepatocellular Carcinoma
SONG Li,TONG Xiao-qiang,WANG Jian,YANG Min,LV Yong-xing,ZOU Ying-hua.Effect of RFA combined with TACE for Primary Hepatocellular Carcinoma[J].Contemporary Medicine,2009,15(23):404-406.
Authors:SONG Li  TONG Xiao-qiang  WANG Jian  YANG Min  LV Yong-xing  ZOU Ying-hua
Institution:SONG Li,TONG Xiao-qiang WANG Jian,YANG Min,LV Yong-xing,ZOU Ying-hua Department of interventional radiology , vascular surgery,Peking University 1st Hospital,Beijing 100034
Abstract:Objectives: To investigate the efficacy and safety of RFA in treating primary hepatocellular carcinoma. Methods: Eighty-one patients with total 114 tumors were treated with radiofrequency ablation combined with TACE. Preoperative and postprocedural CT scans were taken in all patients. During follow-up patients underwent enhanced CT in every 2-3 month interval. Results: Median following-up duration was 30 ± 10.9months (17-49). The median survival time was 34 monthes (95%CI: 18-49 mo.).1-,2and 3-year survival rate was 96.6%, 93.2% and 68.2%, respectively. 57 patients who were still alive when following-up ended. Conclusions: Radiofrequency ablation combined with TACE is effective and reliable in treating primary hepatocellular carcinoma. It may prolong the survival of the patients.
Keywords:radiofrequency ablation  primary hepatocellular carcinoma  
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