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林下参化学成分的研究
引用本文:李海军,刘金平,卢丹,明磊,王鹏,李平亚. 林下参化学成分的研究[J]. 中国实验方剂学杂志, 2010, 16(11): 38-40
作者姓名:李海军  刘金平  卢丹  明磊  王鹏  李平亚
作者单位:吉林大学再生医学科学研究所,长春,130021
基金项目:十一五国家科技支撑计划 
摘    要:目的:研究林下参的化学成分。方法:利用HPLC法对化合物进行分离,通过TLC和NMR等波谱学方法鉴定化合物的结构。结果:从林下参75%乙醇提取液的正丁醇萃取部分分离得到8个化合物,分别鉴定为:20(S)-原人参二醇(1)、人参皂苷Rc(2)、20(S)-人参皂苷Rg2(3)、20(S)-人参皂苷Rg3(4)、20(S)-人参皂苷Rh1(5)、人参皂苷Rb3(6)、20(S)-原人参三醇(7)、人参皂苷Rf(8)。结论:化合物20(S)-原人参二醇、20(S)-原人参三醇和人参皂苷Rf为首次从林下参中分离得到,本研究为综合开发利用林下参资源提供了理论依据。

关 键 词:林下参  人参皂苷  化学成分  分离鉴定
收稿时间:2010-03-25

Studies on Chemical Constituents of Panax ginseng
LI Hai-jun,LIU Jin-ping,LU Dan,MING Lei,WANG Peng and LI Ping-ya. Studies on Chemical Constituents of Panax ginseng[J]. China Journal of Experimental Traditional Medical Formulae, 2010, 16(11): 38-40
Authors:LI Hai-jun  LIU Jin-ping  LU Dan  MING Lei  WANG Peng  LI Ping-ya
Affiliation:Institute of Frontier Medical Science of Jilin University,Changchun 130021, China;Institute of Frontier Medical Science of Jilin University,Changchun 130021, China;Institute of Frontier Medical Science of Jilin University,Changchun 130021, China;Institute of Frontier Medical Science of Jilin University,Changchun 130021, China;Institute of Frontier Medical Science of Jilin University,Changchun 130021, China;Institute of Frontier Medical Science of Jilin University,Changchun 130021, China
Abstract:Objective: To study the chemical constituents of Panax ginseng . Method :The compounds were separated and purified by HPLC and their structures were conformed by TLC and NMR. Result: The structures of eight compounds were conformed, they were 20(S)-protopanaxadiol(1), ginsenoside-Rc(2), 20(S)-ginsenoside-Rg2(3), 20(S)-ginsenoside-Rg3(4), 20(S)-ginseno side-Rh1(5), ginsenoside-Rb3(6), 20(S)-protopanaxatriol(7), ginsenoside-Rf(8). Conclusion: Compound 1, compound 7 and compound 8 were the first found in P. ginseng . This research provided theoretical evidences for the far-reaching use of P. ginseng .
Keywords:Panax ginseng  ginsenoside  chemical constituents  isolation and identification
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