| 培美曲塞/顺铂二线治疗晚期非小细胞肺癌:一例报告及文献复习 |
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| 引用本文： | 赵长林,孙红芹,杨扬,代晓楠.培美曲塞/顺铂二线治疗晚期非小细胞肺癌:一例报告及文献复习[J].中国肺癌杂志,2010,13(7). |
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| 作者姓名： | 赵长林 孙红芹 杨扬 代晓楠 |
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| 作者单位： | 大连大学附属新华医院肿瘤科,大连,116021 |
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| 摘 要： | 背景与目的 结合文献复习,探讨二线治疗晚期非小细胞肺癌的价值.方法 对重组人血管内皮抑制素联合GC方案一线治疗获完全缓解(complete response,CR)后给予吉非替尼维持治疗,无进展生存期(progression free survival,PFS)10.2个月之后进展的1例转移性非小细胞肺腺癌患者,采用培美曲塞/顺铂二线治疗,随访观察患者PFS和生存时间.结果 培美曲塞/顺铂治疗5周期肺原发灶疗效为CR,骨转移灶稳定,PFS为6.6个月,至今已生存22个月,提高了患者的生活质量.结论 晚期非小细胞肺腺癌一线治疗/维持治疗后复发或转移,适时启动培美曲塞/顺铂二线治疗可延长患者生存期,提高生存质量.
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| 关 键 词： | 肺肿瘤 晚期 化学治疗 |
Pemetrexed Combined DDP in the Treatment of Advanced Non-small Cell Lung Cancer: A Case Report and Literature Review |
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| Changlin ZHAO,Hongqin SUN,Yang YANG,Xiaonan DAI.Pemetrexed Combined DDP in the Treatment of Advanced Non-small Cell Lung Cancer: A Case Report and Literature Review[J].Chinese Journal of Lung Cancer,2010,13(7). |
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| Authors: | Changlin ZHAO Hongqin SUN Yang YANG Xiaonan DAI |
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| Institution: | Changlin ZHAO,Hongqin SUN,Yang YANG,Xiaonan DAI Department of Medical Oncology,Xin Hua Hospital Affiliated to Dalian University,Dalian 116021,China |
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| Abstract: | Background and objective The aim of this study is to integrate with literature review, and explore the value of treatment of advanced non-small cell lung cancer with second line. Methods For the metastatic progressive non-small cell lung adenocarcinoma patient, the evaluation of efficacy for complete response (CR) with endostar combined GC, the sequential treatment with gefitinib, used pemetrexed combined DDP as the second line treatment, followed up and observed with the progression free survival (PFS) and... |
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| Keywords: | Lung neoplasms Advanced Chemotherapy |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
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