高血压致颈动脉粥样硬化的作用研究

目的：观察高血压在颈动脉粥样硬化（carotid atherosclerosis,CAS）发生中的重要意义。方法：从2008-10～2009-10内蒙古自治区医院健康体检者和心内科住院病人中筛选正常人群、高血压病人各30例作为研究对象,应用彩色多普勒超声检测所有研究对象的颈动脉内-中膜厚度（intima-media thickness,IMT）和颈动脉粥样斑块的发生率,并进行相关的统计学分析。结果：正常对照组IMT为0.97mm±0.12mm,高血压组IMT为1.08mm±0.16mm,P=0.004,两组间比较有显著统计学差异;正常对照组人中有4人发生颈动脉斑块,高血压组有17人发生颈动脉斑块P=0.001,两组间比较有显著统计学差异。结论：高血压与颈动脉斑块形成及斑块厚度明显正相关,积极控制血压对于减少和减轻颈动脉粥样硬化进程有重要临床意义。

STUDY OF HYPERTENSION EFFECTING THE CAROTID ARTERIOSCLEROSIS

Objective：To investigate the significant meaning of hypertension effecting on carotid atherosclerosis.Methods：30 cases of normal cases fromhealthy volunteers and 30 cases were selected and patients with hypertension in Inner Mongolia Hospital from oct.2008 ～oct.2009.To detect carotid artery intima-media thickness （IMT） using Color doppler ultrasound and calculate the incidence of plaque for everyone. Datas were analysed by related statistical methods.Results：The IMTvalues in normal group is0.97±0.12mm and 1.08±0.16mm in pure hypertension group （P0.01）.there are 4 cases having carotid artery plaque in normal group. However the number is 17 in hypertension group（P0.01）.Conclusions：Hypertension have an important role in induceding CAS. It is more significant that decreased blood pressure and can slowed down the process of atherosclerosis.