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胰岛素样生长因子系统与多囊卵巢综合征关系研究进展
引用本文:陈秀娟,赵杰,刘芳. 胰岛素样生长因子系统与多囊卵巢综合征关系研究进展[J]. 内蒙古医学院学报, 2011, 33(3): 256-259
作者姓名:陈秀娟  赵杰  刘芳
作者单位:内蒙古医学院附属医院,妇产科生殖中心,内蒙古,呼和浩特,010050
基金项目:内蒙古自然科学基金项目
摘    要:
胰岛素样生长因子(insulin-like growth factor,IGF)系统由具有特定功能的配体、受体和结合蛋白组成,在正常生理活动中有极为重要的意义。现已发现,许多疾病如糖尿病、胰岛素抵抗、内分泌紊乱、癌症、营养不良和多囊卵巢综合征(polycystic ovary syndrome,PCOS)等与IGF系统密切相关。体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)助孕治疗中,多囊卵巢综合征病人易发生卵巢过度刺激综合征(ovarian hyperstimulation syndrome,OHSS),IGF系统在OHSS的发生中起一定的作用。

关 键 词:胰岛素样生长因子  多囊卵巢综合征  体外受精-胚胎移植  卵巢过度刺激综合征

THE PROGRESSION OF INSULIN-LIKE GROWTH FACTOR SYSTEM AND ITS ROLE IN THE POLYCYSTIC OVARY SYNDROME
CHEN Xiu-juan,ZHAO Jie,LIU Fang. THE PROGRESSION OF INSULIN-LIKE GROWTH FACTOR SYSTEM AND ITS ROLE IN THE POLYCYSTIC OVARY SYNDROME[J]. Acta Academiae Medicinae Neimongol, 2011, 33(3): 256-259
Authors:CHEN Xiu-juan  ZHAO Jie  LIU Fang
Affiliation:(Department of Obsterics and Gynecology,Affiliated Hospital,Inner Mongolia Medical College,Hohhot 010050 China)
Abstract:
The insulin-like growth factor(IGF) system is ubiquitous and plays important role in every tissue of the body.There are now numerous examples o fdiseases such as polycystic ovary syndrome,diabetes,cancer and malnutrition in which the IGF system is a major player.the IGF system plays a role in ovarian hyperstimulation syndrome(OHSS) in vitro fertilization and embryo transfer(IVF-ET).
Keywords:Insulin-like growth factor system  polycystic ovary syndrome  in vitro fertilization and embryo transfer  ovarian hyperstimulation syndrome
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