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Carotid artery intima-media thickness and elasticity in relation to glucose tolerance |
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| Authors: | Kalle Sipil? Mika K?h?nen Veikko Salomaa Markku P?iv?nsalo Hannu Karanko Marjut Varpula Antti Jula Risto Kaaja Y. Antero Kes?niemi Antti Reunanen Leena Moilanen |
| Affiliation: | 1. Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland 2. Department of Clinical Physiology, University of Tampere, Tampere, Finland 3. Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland 4. Institute of Diagnostics, Department of Radiology, University of Oulu, Oulu, Finland 5. Population Studies Unit, National Institute for Health and Welfare, Turku, Finland 6. Department of Internal Medicine, Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland 7. Department of Obstetrics and Gynaecology, Satakunta Central Hospital, Pori, Finland 8. Department of Obstetrics and Gynaecology, University of Turku, Turku, Finland 10. Clinical Research Center, Oulu University Hospital, Oulu, Finland 9. Institute of Clinical Medicine, Department of Internal Medicine and Biocenter Oulu, University of Oulu, Oulu, Finland 11. Department of Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland |
| Abstract: | The association between diabetes and subclinical atherosclerosis is well established. The effect of non-diabetic glucose intolerance on early atherosclerosis is not as straightforward, and the data regarding sex-related differences in this matter are limited. Therefore, our aim was to investigate these associations in men and women separately. We studied 1,304 Finnish men and women over 45?years of age who participated in the Finnish Health 2000 Survey. Ultrasonically determined carotid artery intima-media thickness and elasticity were used as markers of early atherosclerosis. Glucose tolerance was categorized according to the American Diabetes Association criteria for diabetes mellitus. Age-adjusted means for carotid artery intima-media thickness and elasticity indices were significantly (P?P? |
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