纳米碳示踪技术在甲状腺癌手术中对甲状旁腺的保护作用

目的:探讨纳米碳示踪技术在甲状腺癌手术中对甲状旁腺的保护作用。方法:将50例甲状腺癌患者随机分为常规组(对照组)和纳米碳组(观察组),比较2组淋巴脂肪组织中误切的甲状旁腺检获、术后血钙和甲状旁腺素改变的情况及术后甲状旁腺损伤出现临床症状的发生率。结果:观察组患者术后所有黑染组织病检均未发现甲状旁腺,甲状旁腺受损的有关临床症状发生率均低于对照组(P<0.05~P<0.01),术后第1天、第3天和3个月血钙和甲状旁腺激素水平均高于对照组(P<0.05~P<0.01)。结论:甲状腺与甲状旁腺的淋巴引流途径不同,采用甲状腺淋巴系统的纳米碳示踪可以很好地鉴别出甲状旁腺,降低甲状腺癌淋巴清扫术中甲状旁腺的损伤概率。

The protective effect of the carbon nano technology on the parathyroid during the operation of thyroid cancer

Objective:To explore the protective effects of the nano carbon technology on the parathyroid during the operation of thyroid cancer. Methods:Fifty patients with thyroid carcinoma were randomly divided into the control group and nano carbon group. Parathyroid mistakenly cut in the lymph adipose tissue,postoperative blood calcium and parathyroid hormone levelss,and the incidence of clinical symptoms of postoperative parathyroid injury between two groups were compared. Results:The parathyroid gland in black dye organization in nano carbon group was not found. The incidence of postoperative clinical symptoms of parathyroid damage in nano carbon group was less than that in control group(P<0. 05 to P<0. 01). The levels of blood calcium and parathyroid hormone in nano carbon group were higher than those in control group at d 1,d 3 and 3 months of operation(P <0. 05 to P <0. 01). Conclusions:The lymphatic drainage way of thyroid and parathyroid is different. The nano carbon tracer in thyroid lymphatic system can well identify parathyroid gland,reduce the damage probability of parathyroid gland during the thyroid cancer lymph node cleaning.