| 红花和甘草黄酮的协同抗炎镇痛作用分析 |
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| 引用本文： | 安晓晶,王晓娜,马成俊,李刚,王振华.红花和甘草黄酮的协同抗炎镇痛作用分析[J].甘肃中医,2012,25(10):20-22. |
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| 作者姓名： | 安晓晶 王晓娜 马成俊 李刚 王振华 |
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| 作者单位： | 安晓晶 (石河子大学药学院新疆特种植物药资源教育部重点实验室,新疆,石河子,832002) ； 王晓娜 (石河子大学药学院新疆特种植物药资源教育部重点实验室,新疆,石河子,832002) ； 马成俊 (烟台大学海洋学院) ； 李刚 (烟台大学海洋学院) ； 王振华 (石河子大学药学院新疆特种植物药资源教育部重点实验室,新疆,石河子,832002) ； |
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| 摘 要： | 通过醋酸致小鼠扭体、血管通透性、血栓形成实验考查红花和甘草黄酮的抗炎镇痛作用。发现单独应用红花或甘草，无明显抗炎镇痛活性，两者联合应用抗炎镇痛活性明显增强，表明两种联用，具有明显的协同作用，且两者按1：1比例组方时活性最强。此外还初步研究了其优选组方制备成凝胶剂的抗炎镇痛活性。
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| 关 键 词： | 静脉炎 红花 甘草黄酮 |
Analysis of Synergistic Effect on Anti-inflammation and Analgesia of Red Flower and Licoflavone |
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| AN Xiao-jin,WANG Xiao-na,MA Cheng-jun,LI Gang,WANG Zhen-hua.Analysis of Synergistic Effect on Anti-inflammation and Analgesia of Red Flower and Licoflavone[J].Gansu Journal of Traditional Chinese Medicine,2012,25(10):20-22. |
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| Authors: | AN Xiao-jin WANG Xiao-na MA Cheng-jun LI Gang WANG Zhen-hua |
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| Institution: | Key Laboratory of Phytomedicine Resources and Modernization of TCM in School of Pharmacy of Shihezi University, Shihezi 832002, China; 2 Ocean School of Yantai University |
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| Abstract: | Anti-inflammation and analgesia of red flower and licoflavone was investigated through the experiments of body torsion induced by acetic acid, vasopermeability and thrombosis. It was found that application of red flower or licorice didn＇t show remarkable anti-inflammatory and analgesic function separately, application of both suggested notable anti-inflammatory and analgesic function, which demonstrated that united application showed significant synergistic effect, and when the ratio was 1：1, they had the strongest active. In addition, anti-inflammatory and analgesic effects of optimized formula were initially studied. |
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| Keywords: | phlebitis red flower licoflavone |
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