我院住院患者痰培养病原菌菌谱和耐药性研究

目的:研究我院住院患者痰培养病原菌菌谱和耐药性。方法:对来自我院2005年1月～2007年7月住院患者6052份合格痰标本中培养的2255株病原菌药敏试验进行回顾性分析。结果:2255株病原菌中,革兰阴性杆菌1210株,占53.7%,主要为铜绿假单胞菌、鲍曼不动杆菌、肺炎克雷伯菌、大肠埃希菌,分别占19.5%、13.9%、8.2%、6.4%;革兰阳性球菌429株,占19.0%,主要为凝固酶阴性葡萄球菌、金黄色葡萄球菌;真菌519株,占23.0%,主要为白色念珠菌。结论:革兰阴性杆菌及革兰阳性球菌对相当多数的抗生素耐药率较高。

Species and Drug Resistance of the Bacteria Isolated from Sputum Specimens of Inpatients in Our Hospital

OBJECTIVE:To study the species and drug resistance of the bacteria isolated from sputum specimens of the inpatients in our hospital.METHODS:The drug susceptibility of 2 255 strains of pathogenic bacteria cultured from 6 052 qualified sputum specimens that collected from inpatients of our hospital between Jan.2005 and July 2007 were analyzed retrospectively.RESULTS:Of the 2 255 strains of pathogenic bacteria,1 210(53.7%)were gram negative bacillus,with Pseudomonas aeruginesa,Escherichia cob,Klebsiella pneumoniae and Acinetobacter showing the highest proportion,accounting for 19.5%,13.9%,8.2% and 6.4%,respectively;429(19.0%)were gram positive coccus,with CN-S and Staphylococcus aureus showing the highest proportion;and the 519(23.0%)were fungus with Candida albicans showing the highest proportion.CON-CLUSION:The result of drug susceptibility test showed that both gram negative bacilli and gram positive coccus were highly resistant to quite a few of antibiotics.