四川某医学院新生乙肝病毒感染的血清学调查

目的]了解新生乙肝病毒感染情况,为乙肝的防治采取有效措施提供依据。方法]采用ELISA和PCR方法,对2006年秋季入学的1527名新生进行5项血清HBV标志物（两对半）检测和HBV-DNA定量及定性检查。结果]入校新生HBsAg阳性55人,阳性率3.67%,男生24人,占43.6%;女生31人,占56.4%,大三阳者21名;阳性率为1.38%,男生10人,占47.6;女生11人,占52.4,小三阳者18名,阳性率为1.12%,男生8人,占44.4%;女生10人,占55.6%,其中HBV-DNA阳性11人,占61.1%。结论]高校应对入学新生进行HBV的相关检查;对易感者进行乙肝疫苗的接种,在学生中进行乙肝知识的健康教育以保护易感人群。

ANALYSIS OF HBV INFECTION OF FRESHMEN IN ONE MEDICAL COLLEGE IN SICHUAN

Objective]To know the situation of HBV infection among college freshmen in order to take effective measures for its control and prevention.Methods]1 527 freshmen were tested by ELISA for HBV,including HBsAg,HBsAb,HbeAg,HBcAb,and PCR was adoped as well for HBV-DNA.Results]55 students were detected as HBsAg positive,and the positive rate was 3.67%.There were 21 students being HBsAg,HBeAg and HBcAb positive,18 cases being HBsAg,HBeAb and HBcAb positive,with 11 students being HBV-DNA positive.Conclusion]A large number of college freshmen are at the risk of being infected,therefore,vaccination to HBV and the awareness of the disease are of great significance in the prevention of the wide spread of HBV infection.