Clinical and pathological heterogeneity in cutaneous gamma-delta T-cell lymphoma: a report of three cases and a review of the literature |
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| Authors: | S.E. MUNN,J.M. McGREGOR, A. JONES,&dagger ,P. AMLOT&Dagger ,M.H.A. RUSTIN,R. RUSSELL JONES,S. WHITTAKER |
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| Affiliation: | Department of Dematology. Ealing Hospital, Middlesex;Department of Dermatology, Royal Free Hospital and Medical School. London;Department of Dermatology Oncology, Royal Free Hospital and Medical School. London;Department of Immunology, Royal Free Hospital and Medical School. London |
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| Abstract: | ![]()
Cutaneous gamma-delta (γδ) T-cell lympboma is rare. Eleven cases have been reported to date including four cases of mycosis fungoides (MF). two of pagetoid reticulosis and five of pleomorphic cutaneous T-cell lymphoma (CTCL). We report three further cases of cutaneous γδ T-cell lymphoma: one of ME. one of a pleomorpbic CTCL and one of a subcutaneous T-cell iymphoma. Combined data suggest that although cutaneous γδ T-cell iymphomas do not appear to comprise a single clinicopathoiogical entity, they may be associated with aggressive clinical behaviour and a poor prognosis. |
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