新生儿泪囊炎发病危险因素的病例对照研究

【目的】 探讨与新生儿泪囊炎发生有关的危险因素?【方法】 采用病例对照研究方法,收集2011年门诊诊治的新生儿泪囊炎患儿150例及正常对照150例,对照组为非调查因素相同的非新生儿泪囊炎儿童?采用单因素及多因素非条件Logistic回归分析进行新生儿泪囊炎的危险因素分析?【结果】 经过单因素及多因素非条件Logistic回归分析最终筛选出与新生儿泪囊炎发生相关的3个危险因素,分别为孕周小于37周(OR值为4.922),出生体质量大于4 kg(OR值为2.418)和有鼻炎家族史(OR值为2.453)?【结论】 早产?巨大儿以及鼻炎家族史是新生儿泪囊炎的高危因素?

Case-control Study on Risk Factors of Neonatal Dacryocystitis

【Objective】 To investigate the risk factors associated with the occurrence of neonatal dacryocystitis. 【Methods】 A case-control study was conducted. 150 infants with neonatal dacryocystitis and 150 normal control were screened from patients of Guangzhou Women and Children's Medical Center. The Controls were non-neonatal dacryocystitis infants and their non-investigation factors are the same. The risk factors of neonatal dacryocystitis were analyzed by univariate and multivariate unconditional Logistic regression analysis. 【Results】 Three risk factors were screened to be associated with the occurrence of neonatal dacryocystitis, including Gestational age less than 37 weeks (OR, 4,922), birth mass of more than 4 kg (OR, 2.418) and family history of rhinitis (OR, 2.453). 【Conclusion:】 Preterm birth, macrosomia and family history of rhinitis are major risk factors contributing to neonatal dacryocystitis in neonates.