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溶瘤病毒在恶性黑色素瘤中的临床应用进展
引用本文:岳武恒,邹征云.溶瘤病毒在恶性黑色素瘤中的临床应用进展[J].国际免疫学杂志,2017,40(5).
作者姓名:岳武恒  邹征云
作者单位:1. 210008,南京中医药大学中西医结合鼓楼临床医学院肿瘤中心;2. 210008 南京中医药大学中西医结合鼓楼临床医学院肿瘤中心;210008 南京大学医学院附属鼓楼医院肿瘤中心
基金项目:南京市医学科技发展基金(ZKX15012)Key Project Supported by Medical Science and Technology Development Foundation
摘    要:恶性黑色素瘤是临床上较为常见的皮肤黏膜和色素膜恶性肿瘤,尽管我国恶性黑色素瘤发病率较低,但其发病率及死亡率均呈现快速增长态势,且晚期恶性黑色素瘤患者五年生存率仍不理想.随着人们对溶瘤病毒(oncolytic virus,OV)治疗恶性黑色素瘤的基础与临床研究的深入,必将给晚期黑色素瘤患者带来更好的治疗.

关 键 词:恶性黑色素瘤  溶瘤病毒  临床试验

Advances in treatment of malignant melanoma with oncolytic virus
Yue Wuheng,Zou Zhengyun.Advances in treatment of malignant melanoma with oncolytic virus[J].International Journal of Immunology,2017,40(5).
Authors:Yue Wuheng  Zou Zhengyun
Abstract:Malignant melanoma is a common clinical mucosal and pigmentary cell malignancy. Al-though the incidence of malignant melanoma is low in China,but its morbidity and mortality are showing rapid growth trend. The five-year survival rate of advanced malignant melanoma patients is still unsatisfactory. With the progression of the study on oncolytic virus(OV)treatment,we believe that the advanced melanoma patients will be better treated. Here we review the clinical trials of oncolytic virus used in malignant melanoma,and the problems in this area are discussed.
Keywords:Malignant melanoma  Oncolytic virus  Clinical trial
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