原发性输尿管癌的临床特点及诊治要点 |
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引用本文: | 刘多,姚东伟,刘雪军,刘成. 原发性输尿管癌的临床特点及诊治要点[J]. 国际泌尿系统杂志, 2017, 37(3). DOI: 10.3760/cma.j.issn.1673-4416.2017.03.006 |
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作者姓名: | 刘多 姚东伟 刘雪军 刘成 |
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作者单位: | 连云港 连云港市第二人民医院泌尿外科,江苏,222023 |
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摘 要: | 目的 探讨原发性输尿管癌的临床特点及诊治要点.方法 回顾性分析2000年2月至2016年2月本院行手术治疗的41例输尿管癌患者的临床资料及诊疗经过.结果 所有患者中有28例行根治性肾输尿管全切除术,13例患者行保肾手术,肿瘤组织分期为:pTis、pTa、pT1共有24例,pT2有11例、pT3有6例;病理分级结果为:低度恶性潜能尿路上皮乳头状瘤3例,低级别尿路上皮癌18例及高级别尿路上皮癌20例.出现肿瘤复发及转移的患者共15例,共有7例患者死于输尿管癌的多发转移.结论 输尿管癌具有恶性程度高,易复发,易远处转移等特点,诊断主要依靠影像学及细胞病理学检查,根治性肾输尿管全切术是治疗的金标准,保肾手术可选择性应用,中晚期输尿管癌的治疗需要采取综合治疗以提高生存率.
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关 键 词: | 输尿管肿瘤 预后 |
The clinical characteristics and key factors in diagnoses and treatment of primary ureteral carcinoma |
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Abstract: | Objectives To explore the clinical characteristics and key factors in diagnoses and treatment of primary ureteral carcinoma.Methods Forty-one cases of primary ureteral carcinoma who had underwent surgery in our hospital between February 2000 to February 2016 were analyzed retrospectively.Results Twenty-eight patients underwent radical nephroureterectomy,13 patients underwent nephron-sparing surgery.Tumor staging including:24 cases of tumor stage were pTis,pTa and pT1,pT2 had 11 cases,pT3 had 6 cases.Pathological classification results were:3 cases were part of low-grade malignant potential papillary urothelial neoplasm,18 patients were low level urothelial carcinoma and 20 cases belong to high level of urothelial carcinoma.A total of 15 patients had tumor recurrence and metastasis,seven patients were died from lymph node or distant metastasis.Conclusions Ureteral carcinoma is characterized by high malignant degree,easy to relapse,easy to metastasis,the diagnosis mainly depends on imaging and cell pathology examination,radical nephroureterectomy is the gold standard of treatment,nephron-sparing surgery can also be applied to selective patients.Multimodality therapy is essential for middle-advanced stage patients to improve the survival rate. |
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Keywords: | Ureteral Neoplasms Prognosis |
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