深圳市46例成年人麻疹临床特征及流行病学分析

目的探讨成年人麻疹的发病特点和流行特征，为控制成年人麻疹流行提供依据。方法对2000年1月-2005年10月所收集的46例成年人麻疹病例进行回顾分析。结果成年人麻疹的临床特点主要为全身中毒症状较重，体温较高，皮疹典型，肝功能损害较重。患者以外来流动人员为主，平均年龄28．9岁，以3-6月为发病高峰。患者普遍无麻疹痘苗接种史。结论成年人麻疹病情较重，合并症较多，临床症状不典型，易被误诊，建议在做好常规免疫的基础上，对15岁左右的中学生再进行一次强化免疫，以有效解决体内抗体水平随年龄增长而降低的问题。

The clinical features of 46 adult measles and epidemiological analysis in Shenzhen City

Objective To find the clinical and epidemic characteristic of measles in adults and provide theoretic support for measles control. Methods Data relating to 46 measles adult cases were analyzed from Junuary 2000 to October 2005. Results The main clinical characteristics of adult measles eases were serious toxaemia, high temperature, typical tetter and severe liver dysfunction. Most of the patients belonged to floating population with the average age of 28.9 years old. The peak infection was from March to June. And a majority of them never received measles vaccine. Conclusion The measles in adults is serious and may be misdiagnosed as there complications may occur. On the basis of conventional vaccination intensified vaccination be given to children around 15 years old to enhance the antibody level in the children as the antibody level will be reduced along with the growth of children.