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The effects of hydroxyurea on PRV-1 expression in patients with essential thrombocythemia and polycythemia vera
Authors:Johansson Peter  Ricksten Anne  Wasslavik Carina  Johansson Berit  Andréasson Björn
Abstract:
The study was designed to investigate the influence of hydroxyurea (HU) treatment on PRV-1 expression. Eighteen newly diagnosed patients with essential thrombocythemia (ET) or polycythemia vera (PV) were included. HU significantly increased PRV-1 gene expression in the early stage of treatment.
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