骨内和外周静脉途径进行高渗盐液复苏的比较研究

目的：观察骨内输液（IO）和高渗盐液结合在失血性休克复苏时的效果。方法：利用新西兰大白兔建立失血性休克模型，分为IO组和外周静脉（PIV）组，对两组间不同时间点的血压，心率，生化，动脉血气等进行比较分析。结果：IO输入高渗盐液复苏失血性休克的途径和PIV途径的疗效相似。结论：IO和高渗盐液复苏的结合完全可以达到失血性休克复苏急救的要求。

Comparison of resuscitation by hyperosmotic salt fluid through intraosseous and peripheral intravenous infusion

Objective:To observe the effect of combining intraosseous infusion (IO) and hyperosmotic salt fluid in resuscitation of haemorrhagic shock. Methods:Twenty rabbit models of haemorrhagic shock were established. The blood pressure, heart rate, biochemical indexes, artery blood gas analysis, etc . were compared at 3 different time points after infusion between IO and peripheral intravenous infusion groups. Results:The resuscitative effect through IO with hyperosmotic salt fluid was the same as that of the peripheral vascular access. Conclusion:The combination of intraosseous infusion and hyperosmotic salt fluid is effective for resuscitation of haemorrhagic shock.