| 利福平对血清胆红素测定的干扰探讨 |
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| 引用本文： | 黄慧谦,骆子义,刘智,李兵,詹能勇,吕宁,侯志平,聂小英.利福平对血清胆红素测定的干扰探讨[J].检验医学与临床,2008,5(12):726-727. |
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| 作者姓名： | 黄慧谦 骆子义 刘智 李兵 詹能勇 吕宁 侯志平 聂小英 |
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| 作者单位： | 广东省深圳市第三人民医院,518020 |
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| 摘 要： | 目的 探讨利福平对血清胆红素测定的干扰。方法 用亚硝酸钠氧化法测定血清总胆红素（TBIL）、直接胆红素（DBIL）浓度。结果 利福平对TBIL、DBIL测定有正相干扰作用，干扰的程度与加入血清中的利福平的浓度呈线性关系。结论 利福平对亚硝酸钠氧化法测定TBIL、DBIL可产生光学干扰。
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| 关 键 词： | 利福平 血清胆红素 干扰 实验室技术 |
Interference of rifampicin on the determination of serum bilirubin |
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| HUANG Hui-qian,LUO Zi-yi,LIU Zhi,LI Bing,ZAHN Neng-yong,LV Ning,HOU Zhi-ping,NIE Xiao-ying.Interference of rifampicin on the determination of serum bilirubin[J].Laboratory Medicine and Clinic,2008,5(12):726-727. |
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| Authors: | HUANG Hui-qian LUO Zi-yi LIU Zhi LI Bing ZAHN Neng-yong LV Ning HOU Zhi-ping NIE Xiao-ying |
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| Institution: | .( The Third People＇s Hospital of Shenzhen City, Shenzhen 518020, China) |
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| Abstract: | Objective To observe the interference of rifampicin on the determination of serum bilirubin. Methods Serum total bilirubin （TBIL） and direct bilirubin（DBIL） were detected with sodium nitrite oxygenation method. Results Rifampicin interfered with TBIL and DBIL determination positively. There was a linear relationship between the extent of interference and the serum concentration of rifampicin. Conclusion Rifampicin makes optical interference in the determination of TBIL and DBIL with sodium nitrite oxygenation method. |
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| Keywords: | rifampiein serum bilirubin interferenee laboratory technique |
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