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老年消化道恶性肿瘤患者营养不良影响因素分析及肠内外营养支持干预效果
引用本文:张翠翠,赵静. 老年消化道恶性肿瘤患者营养不良影响因素分析及肠内外营养支持干预效果[J]. 肿瘤药学, 2021, 11(6): 769-774
作者姓名:张翠翠  赵静
作者单位:空军军医大学第一附属医院,陕西 西安,710032
摘    要:
目的 分析老年消化道恶性肿瘤患者营养不良的影响因素,并探讨肠内外营养支持的干预效果.方法 选取2017年1月—2019年1月我院收治的消化道恶性肿瘤患者249例,采用患者自评-主观全面评定(PG-SGA)量表评估患者营养状况,统计营养不良的发生情况;多因素Logistic回归分析老年消化道恶性肿瘤患者营养不良的影响因素...

关 键 词:老年  消化道恶性肿瘤  营养不良  影响因素  肠内外营养支持
收稿时间:2020-06-03

Analysis of influencing factors of malnutrition in elderly patients with gastrointestinal malignant tumors and the intervention effects of enteral and parenteral nutrition support
ZHANG Cuicui,ZHAO Jing. Analysis of influencing factors of malnutrition in elderly patients with gastrointestinal malignant tumors and the intervention effects of enteral and parenteral nutrition support[J]. Anti-Tumor Pharmacy, 2021, 11(6): 769-774
Authors:ZHANG Cuicui  ZHAO Jing
Affiliation:First Affiliated Hospital of Air Force Military Medical University, Xi''an, Shaanxi, 710032, China
Abstract:
Objective To analyze the influencing factors of malnutrition in elderly patients with gastrointestinal malignant tumors, and to explore the effects of enteral and parenteral nutrition supports.Methods A total of 249 patients with gastrointestinal malignant tumors admitted to our hospital between January 2017 and January 2019 were selected. The Patient-Generated Subjective Global Assessment (PG-SGA) scale was used to assess the nutritional status of patients, and the incidence of malnutrition was counted. Multivariate Logistic regression was used to analyze the influencing factors of malnutrition. Enteral and parenteral nutrition supports were given to malnourished patients, and the changes of nutrition indicators, immune function indicators, and quality of life before and after intervention were compared.Results Among the 249 patients, 167 cases had malnutrition, and the incidence rate was 67.07%. Multivariate Logistic regression analysis showed that age (OR=0.681, 95% CI=1.418~3.613), BMI (OR=6.451, 95% CI=4.253~8.212), previous malnutrition (OR=1.631, 95% CI=3.219~6.032) were independent influencing factors of malnutrition in elderly patients with gastrointestinal malignant tumors (P<0.05). After enteral and parenteral nutrition intervention, the nutritional indicators, immune function indicators and quality of life of patients were significantly improved (P<0.05).Conclusion There are many factors resulting in malnutrition in elderly patients with gastrointestinal malignant tumors. Enteral and parenteral nutrition support interventions can effectively improve their nutritional indicators, immune function, and improve the quality of life.
Keywords:Elderly  Gastrointestinal malignant tumor  Malnutrition  Influencing factors  Enteral and parenteral nutrition support
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