Physical and chemical stability of drug nanoparticles |
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Authors: | Wu Libo Zhang Jian Watanabe Wiwik |
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Affiliation: | MAP Pharmaceuticals, Inc. 2400 Bayshore Parkway, Mountain View, CA 94043, USA |
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Abstract: | As nano-sizing is becoming a more common approach for pharmaceutical product development, researchers are taking advantage of the unique inherent properties of nanoparticles for a wide variety of applications. This article reviews the physical and chemical stability of drug nanoparticles, including their mechanisms and corresponding characterization techniques. A few common strategies to overcome stability issues are also discussed. |
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Keywords: | Drug nanoparticles Nanosuspensions Physical stability Chemical stability Stabilizer |
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