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Physical and chemical stability of drug nanoparticles
Authors:Wu Libo  Zhang Jian  Watanabe Wiwik
Affiliation:
  • MAP Pharmaceuticals, Inc. 2400 Bayshore Parkway, Mountain View, CA 94043, USA
  • Abstract:
    As nano-sizing is becoming a more common approach for pharmaceutical product development, researchers are taking advantage of the unique inherent properties of nanoparticles for a wide variety of applications. This article reviews the physical and chemical stability of drug nanoparticles, including their mechanisms and corresponding characterization techniques. A few common strategies to overcome stability issues are also discussed.
    Keywords:Drug nanoparticles   Nanosuspensions   Physical stability   Chemical stability   Stabilizer
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