宫腔镜子宫内膜息肉电切术后应用曼月乐预防复发的临床观察

[目的] 探讨子宫内膜息肉经宫腔镜手术治疗后应用左炔诺孕酮宫内缓释系统(商品名曼月乐)预防复发的临床效果。[方法] 应用宫腔镜对120例子宫内膜息肉患者实行电切除术,术后随机分为治疗组60例和对照组60例,治疗组术后放置曼月乐,对照组不应用任何治疗。随访4年后,观察两组患者的子宫内膜息肉复发情况。[结果] 治疗组子宫内膜息肉复发率为1.6%,对照组为15.0%,两组差异有统计学意义(P<0.05)。[结论] 宫腔镜可对子宫内膜息肉做出较明确的诊断及治疗,术后应用曼月乐治疗有助于预防子宫内膜息肉的复发。

Clinical observation of the effect of levonorgestrel-releasing intrauterine system(LNG-IUD) on pre-venting recurrence after hysteroscopic resection of endometrial polyps

[Objective] To evaluate the clinical effect of LNG-IUD on preventing recurrence after hysteroscopic resection of endometrial polyps. [Methods] Electrical excision of endometrial polyps with the help of hysteroscopy was performed for 120 patients,who were randomly divided into trial group（ levonorgestrel-releasing intrauterine system after surgery） and control group（ without any treatment after surgery）,with 60 patients in each group. After follow-up of 4 years,the recurrence of endometrial polyps was observed in the two groups. [Results] The recurrence rate of trial group was 1. 6%,and that of control group was 15. 0%. There was significant difference in recurrence between the two groups（ P〈0.05）. [Conclusion] The hysteroscopy can be used for more definite diagnosis and treatment of endometrial polyps. And there has been a significantly positive effect of LNG-IUD proved on preventing recurrence after hysteroscopic resection of endometrial polyps.