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Effects of AMG 145 on Low-Density Lipoprotein Cholesterol Levels : Results From 2 Randomized,Double-Blind,Placebo-Controlled,Ascending-Dose Phase 1 Studies in Healthy Volunteers and Hypercholesterolemic Subjects on Statins
Authors:Clapton S. Dias  Adam J. Shaywitz  Scott M. Wasserman  Brian P. Smith  Bing Gao  Dina S. Stolman  Caroline P. Crispino  Karen V. Smirnakis  Maurice G. Emery  Alexander Colbert  John P. Gibbs  Marc W. Retter  Blaire P. Cooke  Stephen T. Uy  Mark Matson  Evan A. Stein
Affiliation:? Medical Sciences, Amgen, Thousand Oaks, California; Global Development, Amgen, Thousand Oaks, California; Biostatistics, Amgen, Thousand Oaks, California;§ Global Safety, Amgen, Thousand Oaks, California; Pharmacokinetics and Drug Metabolism, Amgen, Thousand Oaks, California; Prism Research, St. Paul, Minnesota;# Metabolic and Atherosclerosis Research Center, Cincinnati, Ohio
Abstract:
Keywords:hypercholesterolemia   LDL-C   PCSK9
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