Insulin secretion and pancreatic exocrine function in patients with chronic pancreatitis |
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| Authors: | W. J. Kalk Dr. A. I. Vinik W. P. U. Jackson S. Bank |
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| Affiliation: | (1) Endocrine and Diabetes Research Group of the University of Cape Town Medical School and Groote Schuur Hospital, Cape Town, South Africa;(2) University of Michigan Medical Center, 48109 Ann Arbor, MI, USA |
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| Abstract: | ![]()
Summary The relationship between insulin responses to oral glucose and pancreatic exocrine function were examined in 15 patients with chronic pancreatitis. Good correlations were found between the insulin responses and exocrine pancreatic function measured as the concentrations of pancreatic enzymes in duodenal juice after intravenous cholecystokinin-pancreazymin (CCK-PZ). There appears to be a roughly parallel loss of endocrine and exocrine function in the course of chronic pancreatitis. |
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| Keywords: | Cholecystokinin-pancreazymin diabetes insulin pancreatitis pancreatic function tests secretin |
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