扩大根治性切除治疗胰头癌

目的探讨胰腺癌扩大根治性切除术治疗胰头癌的疗效。方法采用回顾性临床对照研究,将75例实施胰十二指肠切除的胰头癌患者按手术曰期分为对照组(n=38)和研究组(n=37),比较两者的生存率、手术并发症发生率、围手术期死亡及复发率。结果对照组和研究组的手术并发症发生率分别为60.53%和29.73%;3年生存率分别为15.79%和35.14%;3年复发率分别为78.95%和35.14%。差异均有统计学意义(P0.05)。围手术期病死率分别为5.26%和2.70%(P0.05)。结论扩大根治性胰十二指肠切除术能降低胰头癌术后复发率,提高3年生存率。

Extended pancreaticoduodenectomy for carcinoma of head of pancreas

Objective：To study the effect of extended Whipple′s resection for carcinoma of head of pancreas.
Methods：Seventy-five patients who underwent surgery for carcinoma of head of pancreas were divided into control group (traditional Whipple′s operation,n=38) and study group (extended Whipple′s operation, n=37). The survival, complication, mortality and recurrence rates were compared between the 2 groups.
Results：In control group and study group, the complication rate was 60.53%and 29.73%;  the  mortality rate was 5.26% and 2.70%; the recurrence rate was 78.95% and 35.14%; and 3-year survival rate was 15.79% and 35.14%, respectively.
Conclusions：Extended Whipple′s resection for carcinoma of head of pancreas can decrease postoperative recurrence rate and  increase 3-year survival rate.