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A phase I/II study of bevacizumab,irinotecan and erlotinib in children with progressive diffuse intrinsic pontine glioma |
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| Authors: | El-Khouly Fatma E. Veldhuijzen van Zanten Sophie E. M. Jansen Marc H. A. Bakker Dewi P. Sanchez Aliaga Esther Hendrikse N. Harry Vandertop W. Peter van Vuurden Dannis G. Kaspers Gertjan J. L. |
| Affiliation: | 1.Emma Children’s Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Pediatric Oncology, Amsterdam, The Netherlands ;2.Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands ;3.Erasmus MC, Department of Radiology & Nuclear Medicine, Rotterdam, The Netherlands ;4.Wilhelmina Children’s Hospital, Department of Immunology, Utrecht, The Netherlands ;5.Emma Children’s Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Child Neurology, Amsterdam, The Netherlands ;6.Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Radiology & Nuclear Medicine, Amsterdam, The Netherlands ;7.Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Clinical Pharmacology & Pharmacy, Amsterdam, The Netherlands ;8.Amsterdam UMC, Neurosurgical Center Amsterdam, Amsterdam, The Netherlands ; |
| Abstract: | Journal of Neuro-Oncology - This study investigates the safety, tolerability, and preliminary efficacy of combined treatment with VEGF inhibitor bevacizumab, topoisomerase I inhibitor irinotecan,... |
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