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Defining Clinical and Immunological Predictors of Poor Immune Responses to COVID-19 mRNA Vaccines in Patients with Primary Antibody Deficiency
Authors:Shin  Junghee Jenny  Par-Young  Jennefer  Unlu  Serhan  McNamara  Andrew  Park  Hong-Jai  Shin   Min Sun  Gee   Renelle J.  Doyle  Hester  Afinogenova  Yuliya  Zidan  Elena  Kwah  Jason  Russo  Armand  Mamula  Mark  Hsu  Florence Ida  Catanzaro   Jason  Racke   Michael  Bucala   Richard  Wilen   Craig  Kang   Insoo
Affiliation:1.Section of Rheumatology, Allergy & Immunology, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street, New Haven, Connecticut, 06520, USA
;2.Quest Diagnostics, 500 Plaza Dr, Secaucus, NJ, 07094, USA
;3.Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, 06516, USA
;4.Department of Internal Medicine, Bridgeport Hospital – Yale New Haven Health, Bridgeport, CT, 06610, USA
;5.Section of Hematology and Oncology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, 06520, USA
;6.Section of Pulmonary, Allergy, Immunology and Sleep Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, 06520, USA
;7.Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut, 06516, USA
;
Abstract:
Journal of Clinical Immunology - Immune responses to coronavirus disease 2019 (COVID-19) mRNA vaccines in primary antibody deficiencies (PADs) are largely unknown. We investigated antibody and CD4+...
Keywords:
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