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我院254例药品不良反应报告分析
引用本文:李军珂,张梅. 我院254例药品不良反应报告分析[J]. 中国药业, 2011, 20(18): 56-57
作者姓名:李军珂  张梅
作者单位:河南省郑州市妇幼保健院药剂科,河南,郑州,450012
摘    要:
目的了解医院药品不良反应(ADR)发生特点及相关因素,为临床安全用药提供参考。方法对医院2007年1月至2010年9月收集的254例药品不良反应报告进行整理、分析。结果 0~10岁人群药品不良反应发生率最高,占43.70%;给药途径以静脉滴注易引发药品不良反应最多,占53.54%;引发药品不良反应的药物以抗微生物药居首位(占41.97%),其次为中药制剂(占33.44%);药品不良反应临床表现以皮肤及其附件损害最为常见,占46.55%。结论药品不良反应的发生与多种因素有关,临床应做好用药监护,加强药品不良反应监测工作,以减少或避免药品不良反应的发生。

关 键 词:药品不良反应  报告  分析

Analysis on Adverse Drug Reaction Reports in 254 Cases
Li Junke,Zhang Mei. Analysis on Adverse Drug Reaction Reports in 254 Cases[J]. China Pharmaceuticals, 2011, 20(18): 56-57
Authors:Li Junke  Zhang Mei
Affiliation:(Department of Pharmacy,Zhengzhou Maternal and Child Care Hospital,Zhengzhou,Henan,China 450012)
Abstract:
Objective To study the characteristics and the related factors of adverse drug reactions(ADR) occurred in our hospital and to provide reference for clinical medication safety.Methods The retrospective analysis was performed to analyze 254 ADR cases reported in our hospital from Jan.2007 to Sep.2010.Results The crowd aged 0-10 years had the highest ADR incidence(43.70%).Intravenous drip was most likely to lead to ADR,accounting for 53.54%.Anti-microbial drugs ranked first in drugs causing ADR(41.97%),followed by traditional Chinese medicine preparations(33.44%).The clinical manifestations of ADR were mainly the damages of skin and its annexes(46.55%).Conclusion The occurrence of ADR is related with various factors.The medication monitoring should be performed well to strengthen the monitoring of ADR for reducing or avoiding the occurrence of ADR.
Keywords:adverse drug reaction  report  analysis
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