| 80例肾移植患者他克莫司血药浓度数据分析 |
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| 引用本文： | 任斌,黎曙霞,洪晓丹,唐蕾,姚秋燕,黄碧莹.80例肾移植患者他克莫司血药浓度数据分析[J].中国药房,2004,15(11):682-683. |
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| 作者姓名： | 任斌 黎曙霞 洪晓丹 唐蕾 姚秋燕 黄碧莹 |
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| 作者单位： | 中山大学附属第一医院药学部,广州市,510080 |
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| 摘 要： | 目的探讨肾移植患者他克莫司血药浓度与效应关系,定性分析影响他克莫司血药浓度的各种因素。方法收集我院2000年～2001年80例肾移植患者他克莫司血药浓度达稳态后谷浓度数据,并作回顾性分析。结果与结论他克莫司有效血药浓度与疗程有关,肾移植术后2wk内,他克莫司血药浓度宜为12～15ng/ml,2wk以后应为8～15ng/ml。
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| 关 键 词： | 他克莫司 肾移植 血药浓度 |
| 文章编号： | 1001-0408(2004)11-0682-02 |
| 修稿时间： | 2003年11月6日 |
Analysis of Blood Concentration Data of Tacrolimus in 80 Renal Transplantation Patients |
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| REN Bin,LI Shuxia,HONG Xiaodan,TANG Lei,YAO Qiuyan,HUANG Biying.Analysis of Blood Concentration Data of Tacrolimus in 80 Renal Transplantation Patients[J].China Pharmacy,2004,15(11):682-683. |
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| Authors: | REN Bin LI Shuxia HONG Xiaodan TANG Lei YAO Qiuyan HUANG Biying |
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| Abstract: | OBJECTIVE:To investigate the relationship between Tacrolimus blood concentration and effectiveness after renal transplantation and to find factors affecting Tacrolimus blood concentration METHODS:Steady-state trough concentrations of Tacrolimus were collected from 80 renal transplantation patients RESULTS:The effective blood concentration of Tacrolimus was associated with course of treatment CONCLUSIONS:The therapeutic concentration of Tacrolimus was between 12ng/ml and 15ng/ml during the first 2 weeks after renal transplantation,then should be 8ng/ml～15ng/ml |
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| Keywords: | Tacrolimus renal transplantation blood concentration |
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